The cornea is a curved and transparent structure that provides the initial focusing of a light image into the eye. It consists of a central stroma that constitutes 90% of the corneal depth, covered anteriorly with epithelium and posteriorly with endothelium. Its transparency is the result of the regular spacing of collagen fibers with remarkably uniform diameter and interfibrillar space. Cornea...

PURPOSE To evaluate the levels of satisfaction among physicians who have undergone corneal refractive surgery. METHODS This study included 212 eyes of 107 consecutive patients who underwent laser in situ keratomileusis or laser sub-epithelial keratomileusis surgery. Patients were divided into two groups: one group of physicians and one group of other healthcare workers (HCWs). The physicians'...

THE normal corneal horizontal diameter is 12 mm. and any value less than 11 mm. is considered to represent the condition of microcornea (Mann, 1958). The term should be applied only to eyes which are normal except for a small cornea. Corneal curvature is increased so that the corneal refraction is usually great, but associated myopia of varying degrees has been observed by Biro (1935), Puglisi-...

Case Reports Case 1, a female child (IV, 3 in Pedigree) born on December 23, 1958, was noticed to have opaque corneae, of sufficient degree to prevent any estimate of the size of the pupils. There was corneal oedema but no appreciable abnormality of the corneal diameter. In the course of a few days the cornea of each eye had become obviously enlarged and a definite buphthalmos had become establ...

PURPOSE To determine peripapillary retinal nerve fiber layer (RNFL) thickness values by three-dimensional optical coherence tomography (3D-OCT) in a normal Iranian population and to evaluate the concordance of these measurements with those obtained by the second generation of optical coherence tomography (OCT II). METHODS In a cross-sectional observational study, 96 normal Iranian subjects 20...

PURPOSE To observe morphologic and histopathologic changes in the midperiphery of the rabbit cornea produced by femtosecond laser-assisted multilayer intrastromal ablation, determine whether this method may be used to correct myopia, and study how the cornea heals when the epithelium is not injured. METHODS The right eyes of 10 New Zealand White rabbits were used for the experiments. A 60-kHz...

Tissue engineering holds great promise for corneal transplantation to treat blinding diseases. This study was to explore the use of natural corneal stroma as an optimal substrate to construct a native like corneal equivalent. Human corneal epithelium was cultivated from donor limbal explants on corneal stromal discs prepared by FDA approved Horizon Epikeratome system. The morphology, phenotype,...

PURPOSE To explore immunologic issues involved in orthotopic corneal xenotransplantation in a discordant combination using guinea pigs as donors and mice as recipients. METHODS Two-millimeter-diameter guinea pig corneal buttons were transplanted into 1.5-mm-diameter graft beds on mouse corneas using 12 interrupted sutures. Eyelids were maintained occluded with tarsorrhaphy except at the times...

PURPOSE To examine the pattern of nerve regeneration within tissue-engineered corneal substitutes grafted into host porcine corneas over a 1-year postoperative period. METHODS Biodegradable corneal substitutes from cross-linked collagen were implanted into the left eyes of 12 pigs by deep lamellar keratoplasty. Regeneration of severed nerves into the central implant region was investigated wi...