Administration in vivo of recombinant interleukin 2 (rIL-2) to mice induces a polyclonal IgM response. When co-administered with a specific antigen, rIL-2 can enhance concentrations of murine IgM antibodies specific for the antigen by fivefold within 7 d of initial treatment. IgM antibodies that are induced after injection of rIL-2 include antibodies specific for J5, a cell wall core lipopolysa...

diagnosis of hepatitis b is routinely based on of serological assay of hepatitis b surface antigen (hbsag). occult hepatitis b virus (hbv) infection is generally defined as the detection of hbv -dna in the serum or tissues of subjects who have negative test for hbsag. transmission of hbv infection has been documented from hbsag negative, anti-hbc positive blood and organ donors. the aim of this...

The review initially provides a short introduction to prostate cancer (PCa) incidence, mortality, and diagnostics. Next, the need for novel biomarkers PCa diagnostics is briefly discussed. core of details about aetiology, alternative available besides specific antigen their biosensing. In particular, low molecular mass biomolecules (ions metabolites) high (proteins, RNA, DNA, glycoproteins, enz...

BACKGROUND AND OBJECTIVES The relationship between hepatocyte expression of hepatitis B virus (HBV) antigens, liver histology and viral replication in asymptomatic subjects with incidental detection of hepatitis B surface antigen (HBsAg) remains unclear. We evaluated the histological activity index (HAI) and hepatocyte expression of viral antigens with replicative status in asymptomatic chronic...

disulphide bridges in carcinoembryonic antigen (Thomas et af. , 1974). When carcinoembryonic antigen modified by treatment with 5.33rnhl-metaperiodate was hydrolysed in oxygen-free conditions and subjected to acid hydrolysis cystine was detected in a subsequent amino acid analysis, whereas only cysteic acid was obtained from carcinoembryonic antigen treated with 0.533 M-metaperiodate. Oxidative...