Mn(12) single-molecule magnets have been dispersed in water through an emulsion-assisted self-assembly method with an improved stability in water, in order to investigate the use of Mn(12) as MRI contrast agents.

This paper presents the BioShuttle platform as a delivery vehicle for transfer of contrast agents and genetic material into target cells, which can be followed by activation of the BioShuttle inside the target cell. Here, we present a transporter system and summarize the findings on transporter use in vivo and in vitro. The results here are limited to examples where cargoes (drugs, genetically ...

Introduction: While several atlases are available depicting the spatial distribution of various parameters either measured with MRI or from histological section, no comparable comprehensive data exists for the distribution of vessels in the rat brain. Angiography is able to use the blood flow in the brain of the living rat to display the largest arteries, while SWI can visualize veins down to m...

This case illustrates that a large zone of signal void can be produced on short relaxation time MR images when gadopentate dimeglumine is injected through an infiltrated intravenous catheter. The authors consider the physics behind this paradoxical decrease in signal intensity where there are high concentrations of gadopentate dimeglumine.

Contrast media is administered to many patients in hospitals nationwide. Although the use of contrast and dyes is widespread and has a well accepted use among the medical profession, contrast-induced nephropathy can be a common and potentially harmful complication. Identifying patients at risk, attempting to minimize risk, and using preventative strategies should be priorities to decrease the h...

A hyperpolarized 129Xe contrast agent composed of many cryptophane-A molecular cages assembled on an M13 bacteriophage has been demonstrated. Saturation of xenon bound in the large number of cryptophane cages is transferred to the pool of aqueous-solvated xenon via chemical exchange, resulting in efficient generation of hyperCEST contrast. No significant loss of contrast per cryptophane cage wa...

Using a language game to elicit short sentences in various information structural conditions, we found that Finnish 4- to 5-year-olds already exhibit a characteristic interaction between prosody and word order in marking information structure. Providing insights into the acquisition of this complex system of interactions, the production data showed interesting parallels to adult speakers of Fin...

A 3-D thick-shell contrast agent dynamics model was developed by coupling a finite volume Navier-Stokes solver and a potential boundary element method flow solver to simulate the dynamics of thick-shelled contrast agents subjected to pressure waves. The 3-D model was validated using a spherical thick-shell model validated by experimental observations. We then used this model to study shell brea...