Contrast-induced nephropathy is a common form of hospital-acquired acute kidney injury. Incidence is low in patients with normal renal function but increases in high-risk patients. Patients with contrast-induced nephropathy have higher in-hospital complication rates and mortality. Critically ill patients have been assumed to be a high-risk group for contrast-induced nephropathy. In the previous...

Contrast-induced nephropathy (CIN) is defined as acute deterioration of renal function after intravascular administration of iodinated contrast agents, in the absence of other causes. Laboratory diagnosis is expressed as an increase in serum creatinine levels of 0.5 mg/dL (or 44 μmol/L) or a 25% or greater relative increase from baseline 48-72 hours after a diagnostic or interventional procedur...

OBJECTIVE This study evaluated the potential effect of hydration intensity on the role of angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) on contrast-induced nephropathy in patients with renal insufficiency. METHODS All eligible patients were included and stratified according to hydration intensity defined as saline hydration volume to body weight tert...

BACKGROUND AND OBJECTIVES Contrast-induced nephropathy is one of the few preventable forms of acute kidney injury. Several pharmacologic agents have been evaluated for the prevention of contrast-induced nephropathy, yet disappointingly, few have been shown conclusively to reduce the risk for this condition. A series of studies have demonstrated that volume expansion, particularly with intraveno...

BACKGROUND Optimal hydration measures to prevent contrast-induced nephropathy are controversial. STUDY DESIGN We conducted a systematic review and meta-analysis using the MEDLINE database (1966 to January 2008), EMBASE (January 2008), and abstracts from conference proceedings. SETTING & POPULATION Adult patients undergoing contrast procedures. SELECTION CRITERIA FOR STUDIES Randomized con...

Objective: A network meta-analysis to compare various statins for the prevention of contrast induced nephropathy (CIN) was performed in patients who underwent coronary angiography (CAG). Methods: Randomized controlled studies with a Modified Jadad score greater than 3 using statins as prevention for contrast induced nephropathy were utilized from the following databases: PubMed, Ovid EMBASE, Co...

Abstract Introduction Acute kidney injury (AKI) due to contrast induced nephropathy (CIN) is a common complication after percutaneous coronary intervention (PCI) in patients with acute syndrome (ACS), and associated prolonged hospitalizations elevated cardio renovascular morbidity. Scientific evidence demonstrates that the mean volume of (VolC) ratio creatinine clearance (CrCl) (VolC/CrCl) are ...

Background: Contrast-induced nephropathy (CIN) is a major side effect of intravenous iodinated contrast and causes both short- and long-term adverse effects. While diagnostic and interventional procedures of brain ischemia are recently advanced, it is necessary to be cautious about its major side effect. Objectives: To evaluate CIN and its risk factors in neurology patients after brain and cer...

BACKGROUND Contrast-induced nephropathy is one of the common causes of acute renal insufficiency after cardiovascular procedures. HYPOTHESIS The objective of this paper was to analyze the published data on the usefulness of N-acetylcysteine in the prevention of contrast-induced nephropathy after these procedures. METHODS Trials were selected if they were prospective, randomized, controlled,...