This paper is a critical analysis of the concept of ontology thus as it is used in computing science. It identifies three main problems with such a concept, two of which are intrinsic to it and one of which is extrinsic, so to speak, being related to the use of ontology in applications. The first problem with ontology is that the only accepted definition of its main artifact is teleological rat...

 The category of the title is called $mathcal{W}$. This has all free objects $F(I)$ ($I$ a set). For an object class $mathcal{A}$, $Hmathcal{A}$ consists of all homomorphic images of $mathcal{A}$-objects. This note continues the study of the $H$-closed monoreflections $(mathcal{R}, r)$ (meaning $Hmathcal{R} = mathcal{R}$), about which we show ({em inter alia}): $A in mathcal{A}$ if and  only if...

Reativadores eficientes de Aceticolinesterase são fundamentais para o desenvolvimento de antídotos contra o envenenamento por pesticidas neurotóxicos e agentes de guerra química. Todavia, o mecanismo da reação de reativação e as características estruturais dos reativadores conhecidos são pouco compreendidos. Com o objetivo de estudar o comportamento dinâmico e o efeito da carga líquida do antíd...

The brain stem pre-Botzinger complex (pre-BC) plays an important role in respiratory rhythm generation. However, it is not clear what function each subpopulation of neurons in the pre-BC serves. The purpose of the present studies was to identify neuronal subpopulations of the canine pre-BC and to characterize the neuronal responses of subpopulations to experimentally imposed changes in inspirat...

The interstitial nucleus of Cajal (INC) is thought to control torsional and vertical head posture. Unilateral microstimulation of the INC evokes torsional head rotation to positions that are maintained until stimulation offset. Unilateral INC inactivation evokes head position-holding deficits with the head tilted in the opposite direction. However, the underlying muscle synergies for these oppo...

Let $kgeq 1$ be an integer, and $G=(V,E)$ be a finite and simplegraph. The closed neighborhood $N_G[e]$ of an edge $e$ in a graph$G$ is the set consisting of $e$ and all edges having a commonend-vertex with $e$. A signed Roman edge $k$-dominating function(SREkDF) on a graph $G$ is a function $f:E rightarrow{-1,1,2}$ satisfying the conditions that (i) for every edge $e$of $G$, $sum _{xin N[e]} f...

Motor training results in encoding of motor memories, a form of use-dependent plasticity. Here we tested the hypothesis that transcranial magnetic stimulation (TMS) synchronously applied to a motor cortex engaged in a motor training task could enhance this plastic process. Healthy volunteers were studied in four sessions: training consisting of performance of directionally specific voluntary th...

This paper is devoted to the concepts of fuzzy upper and fuzzy lower contra-continuous multifunctions and also some characterizations of them are considered.

* Professor Associado, Departamento de Pediatria da Faculdade de Medicina da Universidade de São Paulo. Nesta edição do Jornal de Pediatria, NascimentoCarvalho e cols.1 apresentam o resultado de estudo que avalia as cepas invasivas de pneumococo, isoladas de pacientes com menos de 20 anos de idade, e Lucarevschi e cols.2 apresentam dados sobre a colonização de orofaringe por Streptococcus pneum...