In a prospective study still in progress, infants with congenital cytomegalovirus (CMV) infection were followed with audiological, ophthalmological, neurological, and psychological tests; 10,328 infants were investigated within a 5-year period (1977-1982) by virus isolation in urine within the first week of life. Fifty (0.5%) had a congenital CMV infection. In this group four children turned ou...

A number of viral infections can cause hearing loss. Hearing loss induced by these viruses can be congenital or acquired, unilateral or bilateral. Certain viral infections can directly damage inner ear structures, others can induce inflammatory responses which then cause this damage, and still others can increase susceptibility or bacterial or fungal infection, leading to hearing loss. Typicall...

Survivors of extracorporeal membrane oxygenation (ECMO) therapy and high-frequency oscillatory (HFO) therapy during the newborn period were followed to evaluate their hearing. Eleven of the 66 ECMO survivors (16.7%) were diagnosed with significant hearing loss after being discharged from the neonatal intensive care unit (NICU). This rate of hearing loss is consistent with other reports of heari...

School-based hearing screening programs have been commonplace in the United States since the 1960’s. Historically, the enrollment of children in the public school system afforded the first opportunity to have access to a large population of children in order to screen for hearing disorders. Such programs were primarily designed to identify hearing losses that necessitated medical referral and t...

INTRODUCTION: Large vestibular aqueduct syndrome, or enlarged endolymphatic duct (EED) and sac (EFS) syndrome, is an inner ear malformation which manifests itself as progressive sensorineural hearing loss starting in infancy or childhood. The deformity of the endolymphatic duct and sac is congenital: however, the hearing loss that develops in this syndrome is acquired. A characteristic feature ...

abstract:background : hyperbilirubinemia is one of the most common cause of congenital sensory neuronal hearing loss. these patients are screened by auditory brainstem response (abr) test at bilirubin levels higher than 1% of gestational weight. aim: to determine whether hyperbilirubinemia less than 1% of gestational weight could induce hearing loss and abnormal auditory brainstem response (abr...

Autosomal recessive non-syndromic hearing loss is the most common form of inherited childhood deafness. Identification of the responsible gene in this type of hearing loss presents difficulties because of marked genetic heterogenicity and limited clinical presentation. A two-year-old girl was referred to our clinic because of congenital hearing loss. Family history showed that her brother and s...

Abstract:Background : Hyperbilirubinemia is one of the most common cause of congenital sensory neuronal hearing loss. These patients are screened by auditory brainstem response (ABR) test at bilirubin levels higher than 1% of gestational weight. Aim: to determine whether hyperbilirubinemia less than 1% of gestational weight could induce hearing loss and abnormal auditory brainstem response (ABR...

mutations in the gjb2 gene are the most common known cause of hereditary congenital hearing loss. rapid genomic dna extraction (rgde) method was used for genomic dna extraction. after amplification of coding region of cx26 gene with specific primers, expected pcr products with 724bp length were subjected to direct sequencing in both directions. we describe here a novel heterozygous -t to -c tra...