the aim of the present study was to examine the effect of 8 weeks of concurrent training on the plasma myostatin levels in non-athlete obese men. this research was quasi-experimental. for this purpose, 23 overweight non-athlete men voluntarily participated in this study and were assigned to concurrent training group (n=12, mean age 21.38±2.06 yr, height 173.65±7.07 cm, weight 86.61±15.05 kg and...

The hypothesis was tested that differential, coregulated transcriptional adaptations of various cellular pathways would occur early with increased mechanical loading of atrophied skeletal muscle and relate to concurrent damage of muscle fibers. Atrophy and slow-to-fast fiber transformation of rat soleus muscle was provoked by 14 days of hindlimb suspension (HS). Subsequent reloading of hindlimb...

Tendon attaches to bone across a specialized tissue called the enthesis. This tissue modulates the transfer of muscle forces between two materials, i.e. tendon and bone, with vastly different mechanical properties. The enthesis for many tendons consists of a mineralized graded fibrocartilage that develops postnatally, concurrent with epiphyseal mineralization. Although it is well described that...

Tendon attaches to bone across a specialized tissue called the enthesis. This tissue modulates the transfer of muscle forces between two materials, i.e. tendon and bone, with vastly different mechanical properties. The enthesis for many tendons consists of a mineralized graded fibrocartilage that develops postnatally, concurrent with epiphyseal mineralization. Although it is well described that...

BACKGROUND Phenylketonuria (PKU) is caused by the inherited defect of the phenylalanine hydroxylase enzyme, which converts phenylalanine (Phe) into tyrosine (Tyr). Neonatal screening programs and early treatment have radically changed the natural history of PKU. Nevertheless, an increased risk of neurocognitive and psychiatric problems in adulthood remains a challenging aspect of the disease. I...

Although coordination of concurrent objects is a fundamental aspect of object-oriented concurrent programming, there is only little support for its specification and abstraction at the language level. This is a problem because coordination is often buried in the code of the coordinated objects, leading to a lack of abstraction and reuse. Here we present CoLaS, a coordination model and its imple...

15 December 2012 We consider the problem of sharing retailer’s demand information in a supply chain with two competing manufacturers selling substitutable products through a common retailer. We consider several scenarios with the manufacturers facing either production diseconomy or economy, and the retailer offering information contracts either concurrently or sequentially to the manufacturers....