Deleterious or 'disease-associated' mutations are mutations that lead to disease with high phenotype penetrance: they are inherited in a simple Mendelian manner, or, in the case of cancer, accumulate in somatic cells leading directly to disease. However, in some cases, the amino acid that is substituted resulting in disease is the wild-type native residue in the functionally equivalent protein ...

VDII ~ I A new CMOS buffer is introduced. A compensation circuit is used to cancel the output voltage offset resulting from the body effect. The voltage offset cancellation is achieved over all the input range hence resulting in a highly linear voltage transfer gain, which is independent of process variation. Class AB output stage is used in order to minimize the power consumption and increase ...

This paper deals with the coding of the partition information resulting from the segmentation of video se quences Motion compensation of partition sequences is described as an e cient inter frame mode of coding It involves the prediction of the partition the computation of the partition compensation error the simpli cation of the error and its transmission The major issues and processing steps ...

Video compression has been an active research area in the last decade. Amongst many proposed methods, motion compensated coding has taken the most attention and taken its place in many standards (Mpeg, H.26L, etc...) The main difference between motion compensated coding and image based coding schemes such as DCT is that motion compensated coding exploits temporal redundancies between consecutiv...

Optimality conditions and comparative static properties of the optimal Mirrleesian nonlinear income tax are obtained for a nite population and quasilinear-in-consumption preferences. Contrary to Weymark (1987) who considers quasilinear-in-leisure preferences, the linearity with respect to gross income, which is observed by the government and used as a tax base, is lost. A reduced-form optimal i...

Multihypothesis motion-compensating predictors combine several motion-compensated signals to predict the current frame signal. More than one motion-compensated signal, or hypothesis, is selected for transmission. Long-term memory motion-compensated prediction is a further concept for efficient video compression and is an example for forward-adaptive hypothesis switching. One motion-compensated ...

This article explores the efficiency of motion-compensated three-dimensional transform coding, a compression scheme that employs a motion-compensated transform for a group of pictures. We investigate this coding scheme experimentally and theoretically. The practical coding scheme employs in temporal direction a wavelet decomposition with motion-compensated lifting steps. Further, we compare the...

BACKGROUND Peru has a concentrated HIV epidemic in which men who have sex with men are particularly vulnerable. We describe the lifetime prevalence of same-sex sexual contact and associated risk behaviors of men in Peru's general population, regardless of their sexual identity. METHODS AND RESULTS A probability sample of males from low-income households in three Peruvian cities completed an e...

This paper considers the effects of changes in the income distribution in an economy where agents’ utility depends both on consumption and on their rank in the distribution of consumption of a positional good. We introduce a new methodology to compare the behavior of agents that occupy the same rank in the two different income distributions but typically have different levels of incomes, and an...