OBJECTIVE In this study, we evaluated the frequency of FMS-like tyrosine kinase 3 (FLT3-ITD and FLT3-TKD) and nucleophosmin (NPM1) mutations in Iranian patients with cytogenetically normal acute myeloid leukemia (CN-AML). The clinical and laboratory characteristics were compared between wild-type and mutant cases. MATERIALS AND METHODS Seventy newly diagnosed de novo AML patients were recruit...

The extent of contribution from common gene copy number (CN) variants in human disease is currently unresolved. Part of the reason for this is the technical difficulty in directly measuring CN variation (CNV) using molecular methods, and the lack of single nucleotide polymorphisms (SNPs) that can tag complex CNV that has arisen multiple times on different SNP haplotypes. One CNV locus implicate...

For (c,,..., c„) in C, let C(cx,..., c„) denote the class of functions/(z) = 1 + cxz + ■ ■ • + cnz" + 2*>_„+ia*z* which are analytic and satisfy Re/(z) > 0 in the unit disc. The unique function of least H2 norm in C(cx,. .., c„) is explicitly determined. In this paper we consider a minimal interpolation problem at the origin, for the class H2 n C, where H2 denotes the well-known Hardy space for...

Background and Objective: The increasing demand for the discovery of next-generation antimicrobials necessitates the use of plant extracts as alternatives. This study investigates the antibacterial efficacy of extracted cinnamon essential oil (CEO) and commercial cinnamaldehyde (CN) against foodborne pathogens. Methods: Kirby-Bauer disc diffusion method was used to screen the antimicrobial pot...

Let I=〈f1,…,fm〉⊂Q[x1,…,xn] be a zero dimensional radical ideal defined by polynomials given with exact rational coefficients. Assume that we are approximations {z1,…,zk}⊂Cn for the common roots {ξ1,…,ξk}=V(I)⊆Cn. In this paper show how to construct and certify entries of Hermite matrices I from approximate {z1,…,zk}. When is non-radical, give methods roots. Furthermore, use signatures these cer...

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195pt and 1h nmr has been used to show that addition of chlorine and bromine to [pt(cn)4]2_ in presence of perchloric acid in water results in cyanide and water scrambling with formation of eleven complexes of the type [pt(cn)4-ncl(h2o)n+1](n-1)+ (n=0, 1, 2, 3, 4). addition of nbu4oh to this solution gives (nbu4)2[pt(cn)4cl(oh)]. nmr measurements in acetone also show cyanide and hydroxyl group ...

performance, digestibility of nutrients, microbial nitrogen flow (mnf) and nitrogen efficiency (ne) inearly lactating holstein cows were investigated by diet supplementation with sodium caseinate (cn).multiparous lactating holstein cows (n = 15) with an average body weight of 638 kg and 21 days in milkwere assigned to a completely randomized design (five cows per treatment) and fed a basal diet...

Table A1: At high resolution (∼ 0.3 ˚ A), T98 indices of BSPs obtained with the fitting functions (FFs) method.