نتایج جستجو برای: colorectal cancer

تعداد نتایج: 925796  

ژورنال: مجله علوم پزشکی رازی 2021
Hadad Esfahani, Marzieh, Mohamadynejad, parisa,

Backgrounds: SIRT1 plays an important role in many physiological processes, including metabolism, neuronal protection, senecence and inflammatory, by staging histones and multiple transcription factors. However, the complex mechanisms of SIRT1 signaling in tumors are not yet fully understood, as it acts as both an oncogen and a tumor suppressor. On the other hand, it has been shown that the Lnc...

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Journal: :iranian journal of cancer prevention 0
z allameh dept. of clinical pharmacy, faculty of pharmacy, shahid beheshti university of medical sciences, tehran, iran m davari dept. of clinical pharmacy, faculty of pharmacy, isfahan university of medical sciences, isfahan, iran mh emami dept. of gastroenterology, faculty of medicine, isfahan university of medical sciences, isfahan, iran

background: colorectal cancer is the second cause of the cancer related mortalities in the world. screening can effectively reduce the mortality and morbidity rate of this cancer. sensitivity and specificity of screening methods play an important role in their efficacy. the aim of this study is to review sensitivity and specificity of selected colorectal cancer screening methods systematically....

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Journal: :iranian journal of cancer prevention 0
sr mousavi m talebinfar m zeinalzadeh a saberi a kaviani m aminseresht

abstract: background: the c-reactive protein (crp) is a product synthesized in hepatocytes and has been reported to be up-regulated by such proinflammatory cytokines as interleukin-1 (il-1), interleukin-6 (il-6), and tumor necrosis factor (tnf). the significance of a preoperative serum elevation in crp as a predictive indicator for the malignant potential and prognosis in colorectal cancer has ...

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ژورنال: یافته 2014
قنادی, کورش , عبیداوی, ضیاء , عنبری, خاطره,

Background: The aim of this study was to investigate the relationship of familial history of gastrointestinal cancers and personal history of colon polyps with colorectal cancer incidence in khorramabad in 2012. Materials and Methods: This cross-sectional study included 50 patients with definite diagnosis of colon cancer based on colonoscopy and pathology in 2012. The control group included 56 ...

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ژورنال: مجله دانشگاه علوم پزشکی مازندران 2015
رشیدی, معصومه, برهانی, سمانه, جان بابایی, قاسم, صالحی فر, ابراهیم, میرزایی پور, عبدالباسط, کوچکی, بیژن,

Background and purpose: Colorectal cancer is the fourth most common cancer in Iran. The incidence of this cancer, especially in the northern regions in Iran, has increased in the last two decades. This study was designed to update the demographic and clinical characteristics of patients with colorectal cancer in Mazandaran province. Materials and methods: All patients with diagnosis of colorec...

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Journal: :مجله بین المللی زیست و زیست پزشکی 0
ali asghar ahmadi north research center-pasteur institute of iran, amol, iran mohammad shadifar north research center-pasteur institute of iran, amol, iran ramin ataee thalassemia research center, hemoglobinopathy institiute,mazandaran university of medical sciences, sari, iran cathy vaillancourt inrs- institut armand-frappier, université du québec, laval, qc,canada amin ataee department of pharmacology, babol university of medical sciences, babol, iran talal oufkir pharmaceutical sciences research center, mazandaran university of medical sciences, sari, iran

curcumin exhibits both cancer- preventive activity and growth inhibitory effects on several neoplastic cells including human colon cancer. serotonin and its receptors have also been implicated in tumor development. this study investigated the effect of ritanserin, a selective serotonin 5ht2a receptor antagonist, alone and in combination with curcumin on colorectal cancer cell lines. results sho...

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Journal: :iranian journal of cancer prevention 0
m montazer haghighi r radpour m vahedi sr mohebbi f khatami f derakhshan

abstract: methylenetetrahydrofolate reductase (mthfr) is a key enzyme regulating folate metabolism, which affects dna methylation and synthesis. one of the most important polymorphisms identified in the mthfr gene is c677t. mthfr activity is lowered in individuals with 677tt genotype. using pyrosequencing, we analyzed the mthfr genotypes in 118 colorectal cancer patients and 189 normal matched ...

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ژورنال: مجله علوم پزشکی رازی 2015

 Background: Colorectal cancer is the third current cancer in the world and the forth cause of death in cancers. Certain factors such as environmental, genetic and life style are related with this cancer. The objective of this study is to find the survival of Iranian patients with colorectal cancer and also to find its prognostic factors. Methods: In this survival study, the data was co...

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ژورنال: یافته 2014
شهبازیان, حجت الله, طلایی زاده, عبدالحسن , محمودوند, هرمز,

Background: Colorectal cancer is the most common malignant gastrointestinal cancer and the fourth most common cancer throughout the world. Disease staging is performed to select the treatment method. In this interventional study we evaluated the effect of adjuvant chemotherapy on local recurrence, distant metastasis and three-year disease free survival in patients with stage 2 colorectal cancer...

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Journal: Iranian Biomedical Journal 2015
Behnam Kamalidehghan, Ehsan Khodapasand, Farid Farrokhi, Massoud Houshmand, Narges Jafarzadeh,

Background: Bax and Bcl-2 are the major members of Bcl-2 family whose play a key role in tumor progression or inhibition of intrinsic apoptotic pathway triggered by mitochondrial dysfunction. Therefore, the balance between pro- and anti-apoptotic members of this family can determine the cellular fate. Methods: In this study, the relative level of mRNA expression of Bax and Bcl-2 genes was deter...

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