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background functional constipation (fc) and constipation-predominant irritable bowl syndrome (cibs)are two main subtypes of constipation that can be distinguished by the rome ii criteria. measuring colonic transit time (ctt) is an easy and cost effective way to evaluate constipation. this study was conducted to compare the ctt in patients with fc and cibs. materials and methods those patients w...

conclusions it was shown that combination of pectin and eudragits can relatively control drug release in the upper gi. on the other hand, pectin degraded in the presence of pectinase and formulations were susceptible to the colonic media. results it was shown that in the presence of pectin, formulations without erl had a relative resistance to drug release in sgf. pellets containing pectin and ...

AIM To explore the relationship between colonic secretory function and colonic motility. METHODS Using a rat model chronically implanted with intracerebroventricular (ICV) and cecal catheters, we validated the correlation between colonic secretion and colonic motor functions, as well as the role of ICV injection volume. RESULTS Compared to saline controls (5 μL/rat), ICV acyl ghrelin at 1 n...

Abreu-Martin, Maria T., Andrew A. Palladino, Mary Faris, Nelson M. Carramanzana, André E. Nel, and Stephan R. Targan. Fas activates the JNK pathway in human colonic epithelial cells: lack of a direct role in apoptosis. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G599–G605, 1999.—Fas is expressed constitutively by colonic epithelial cells, and its ligand is expressed by intraepithelia...

BACKGROUND Chronic constipation is one of the most common chronic disease in children. Most of cases are functional, however some has problem of organic myopathic or neuropathic colon. Colonic transit study with oro-anal transit markers is the basic diagnostic tool for colonic dysmotility in clinical practice, colonic manometry is the recommended investigation in the next step. Nevertheless, th...

Ilias Kouerinis, Kipselis 17, 11257 Athens, Greece, e-mail: [email protected] Conversely, several degrees of colonic lesions following pancreatic abscess formation have been described: a) localized paralytic ileus of the transverse colon b) Intramural involvement of the colon in a localized area c) colonic stricture simulating colonic carcinoma d) colonic bleeding e) colonic fistula. The i...