Cell adhesion molecules act as signal transducers from the extracellular environment to the cytoskeleton and the nucleus and consequently induce changes in the expression pattern of structural proteins. In this study, we showed the effect of thyroid hormone (TH) inhibition and arrest of metamorphosis on the expression of E-cadherin, beta-and alpha-catenin in the developing kidney of Bufo arenar...

The aim of this study was to correlate apoptotic cell rate from different nephron segments between control group and groups of patients with Balkan endemic nephropathy (BEN). Kidney specimens of20 patients with clinically and epidemiologically confirmed BEN were compared with biopsy material of 10 patients (group I, non BEN) without glomerular or tubulointerstitial disease. Out of 20 patients w...

PURPOSE Blockage of the urinary tract induces changes in renal structure including tubular dilatation or atrophy, tubular cell death, inflammatory processes, and progressive interstitial fibrosis with the loss of renal parenchyma. The present study was conducted to survey the protective effects of Taxol and taurine on the renal structure after unilateral ureteral obstruction (UUO). MATERIALS ...

The induction of exercise-induced apoptosis in not actively involved in exercise organs, such as kidney could be a result of oxidative stress. Metallothionein (MT) exerts a protective effect in the cell against oxidative stress and apoptosis. We have previously demonstrated an increased incidence of apoptosis in distal tubular cells and collecting ducts in rat kidney after acute exercise. The p...

Sturgeons are ancient and commercial fishes which posses’ primitive characteristics and due to their great inflections are able to live in both freshwater and marine environments. So their kidney has great ability for adaptation process. In order to find the structure and distribution of kidney nephrons in juvenile Huso huso and Acipensr persicus, sampling of head, body and caudal parts of kidn...

To examine the mechanism by which mineralocorticoids regulate HCO3- absorption in the rabbit inner stripe of the outer medullary collecting duct, we microfluorometrically measured intracellular pH (pHi) in in vitro perfused tubules using 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein (BCECF) assaying the apical and basolateral membrane H+/OH-/HCO3- transport processes in three groups of animal...

to determine microscopic structures of nephrons in caspian pony, a total number of five adult and healthy miniature ponies were provided and after opening the abdominal area, the kidneys were removed. the specimens, after fixation in 10% formalin and tissue passages were stained by hematoxylin and eosin and studied under light microscope. kidneys are covered by a dense connective tissue. each k...

In order to study the role of the kidney in fish osmoregulation, freshwater acclimatized juvenile spottedscat (Scatophagus argus L.) were subjected to four different salinities and observed for histomorphometricchanges of the kidney at 1, 2, 10 and 15 days post transfer time points. The overall morphological changesdisplayed by fish kidney included significant decrease in the density of collect...

INTRODUCTION The renin-angiotensin-aldosterone system (RAAS) plays an integral role in the regulation of blood pressure, electrolyte and fluid homeostasis in mammals. The capability of the different nephron segments to form components of the RAAS is only partially known. This study therefore aimed to characterize the nephron-specific expression of RAAS components within the mouse kidney. MATE...