Objectives: Although radiation therapy has been used for more than a hundred years, its definitive mechanism of action is not known. Many studies indicate that induces free radicals which damage DNA. However, irradiation should also affect the collagen connective tissue matrix. This database analysis aims to determine extent DNA versus perception in scientific papers. Methods: Journals indexed ...

Objective: Collagen is one of the main components in connective tissue (CT) and contributes to background toughness beef. It known that living animals, collagen can be degraded remodeled by collagenase matrix metalloproteinases (MMP); however, it unclear if MMP impact CT texture during postmortem aging Therefore, this study aimed understand how activity may degradation beef three different cuts...

This work reports on the development of collagen films with graphene oxide nanoparticles (GO NPs), aiming toward a new generation functional sustainable sensors. For this purpose, different GO NP contents up to 3 wt % were incorporated into matrix, and morphological, thermal, mechanical electrical properties evaluated. Independently content, all display an increase in thermal stability as resul...

Following injury, ligaments and tendons do not regain their normal biological and biomechanical status. This study analyzed whether an injection of human bone marrow stromal cells (BMSC) or human fibroblast in a liquid fibrin matrix influences the histological results, ultrastructural morphology, mRNA expression of essential extracellular matrix proteins, and material properties of the healing ...

PURPOSE To study the effects of collagen matrix and fibroblasts on the growth and development of human bulbar conjunctival epithelial cells. METHOD Human bulbar conjunctival epithelial cells were cultured on three-dimensional collagen gels containing either normal human conjunctival fibroblasts (HCF), Swiss 3T3 cells, or no cells. After 1 week of culturing, half of the cultures were raised to...

Cartilage oligomeric matrix protein (COMP) is a protein present in the cartilage matrix and is expressed more abundantly in osteoarthritis cartilage than in healthy cartilage. The present study was designed to investigate the effect of transforming growth factor β (TGFβ) on COMP deposition and the influence of COMP on collagen biochemistry in a long-term 3-dimensional culture. Bovine chondrocyt...