Fluctuating double vision and ptosis are the hallmarks of extraocular muscle weakness in myasthenia gravis (MG). On sustained upward gaze, ptosis usually increases temporarily. The first description of using this fatigue sign has been attributed to the Scottish neurologist John Simpson. Cogan added his lidtwitch sign to the diagnostic bedside armamentarium.1 For many years, we have applied a fa...

J Nucl Med. H. M. Kantarjian, A. G. Bledin, E. E. Kim, B. M. Cogan, V. P. Chuang, S. Wallace and T. P. Haynie Intra-Arterial Chemotheraphy of Sarcomas Arterial Perfusion with Tc-99m Macroaggregated Albumin (MAAAP) in Monitoring http://jnm.snmjournals.org/content/24/4/297 This article and updated information are available at: http://jnm.snmjournals.org/site/subscriptions/online.xhtml Information...

THE exchange of water between blood and eye fluids is very rapid (Kinsey, Grant, and Cogan, 1942) in comparison with the migration of sodium chloride across the blood aqueous barrier. Consequently, on making the blood hypertonic by the intravenous injection of sodium chloride, water should be withdrawn from the eye, and the intra-ocular pressure lowered. Qualitatively, such an effect has been d...

491 National Tax Journal Vol. LIX, No. 3 September 2006 Abstract This paper analyzes proposals to remedy tax–induced distortions in health care by using new tax incentives and retaining all of the existing distortionary tax incentives. In the process of remedying some distortions, this approach magnifi es others—most notably increasing the total tax preference for health care. The paper conside...

Mr. Cogan and Mr. Johnson discuss the judicial review provisions of the Medicare Act, codified at 42 U.S.C. section 405(g) and (h), and the Supreme Court cases including Illinois Council that interpret the scope of the "arising under" language. They also examine the history of section 205(h) of the Social Security Act, including the most recent amendment contained in the Deficit Reduction Act o...

T, . etrazolium stains permit the histochemical demonstration of dehydrogenase enzymes in tissue sections. These stains are soluble compounds which act as hydrogen acceptors developing insoluble formazan precipitates in the reduced state. Blue tetrazolium was first used by DeBerardinis to study frozen corneal tissue sections and subsequently has been used by Kuwabara and Cogan, who studied the ...

The absorption of photons in rods and cones of the retina activate homologous biochemical signaling cascades that lead to the electrical changes that subserve the first steps in vision. Persistent activity of the cascade interferes with the ability of the photoreceptor to signal the absorption of subsequent photons, ultimately limiting the photoreceptor's sensitivity and temporal resolution. Th...