Introduction: Cochlear noise injury is considered one of the most debilitating diseases worldwide. Numerous drug trials have been made for complete protection from this acoustic trauma, unfortunately with little success. Recently, drug combination has showed promising effects in treating this trauma; however, this has to be further documented by in-depth researches. Aim of the work: To estimate...

objectives: profound hearing loss encounters children with delay in speech and language. as it is known language acquisition in young deaf children is a lengthy process, but cochlear implanted children have better spoken language skills than if they had not received the device. according to the importance of cochlear implant in deaf child's language development, this study evaluates the ef...

Introduction: Serum Anti endothelial Cell Antibodies (AECAs) play a prominent role in idiopathic Sensorineural Hearing Loss (SNHL) in that they induce vascular damage (immune mediated).The of the current study is  To compare AECAs in serum and perilymphatic .uid of idiopathic SNHL children (<15y) undergoing cochlear implant surgery.Methods: This was a cross sectional study performed in the coch...

OBJECTIVES Carboplatin, a platinum-containing anti-cancer drug used to treat a variety of cancers, induces ototoxicity. Since, reactive oxygen species (ROS) and nitric oxide (NO) seem to be responsible for this toxicity, the antioxidant, N-acetyl-L-cysteine (L-NAC), and NO synthetase inhibitor, N-nitro-L-arginine methyl ester (L-NAME) were predicted to have protective effects against carboplati...

Introduction: Cochlear implantation can facilitate the development of communication skills in children with profound hearing loss. The objectives of our study were to determine the average ages at suspicion and diagnosis of hearing loss, amplification, intervention, and performing the cochlear implantation and to investigate the effects of the parents’ level of education and economic circumsta...

Dear Editor, I read with great interest the recent study by Yücedağ et al. [1] entitled " The Effects of Nonylphenol on Hearing in Rats. " It needs to be specified in the article if the hearing levels of the rats were evaluated before the study or not. Another point I would like to emphasize is that the hearing levels of the rats after the application of ethanol and nonylphenol were evaluated b...

Perceptual abnormalities such as hyperacusis and tinnitus often occur after acoustic overexposure. Although such exposure can also result in permanent threshold elevation, some individuals with noise-induced hyperacusis or tinnitus show clinically normal thresholds. Recent work in animals has shown that a "neuropathic" noise exposure can cause immediate, permanent degeneration of the cochlear n...