Cobalt is essential for growth of Salmonella enterica and other organisms, yet this metal can be toxic when present in excess. Wild-type Salmonella exhibits several metabolic defects when grown in the presence of cobalt, some of which generate visible growth consequences. Work herein identifies sulfur assimilation, iron homeostasis, and Fe-S cluster metabolism as targets for cobalt toxicity. In...

β-diketone-cobalt complexes, a family of newly synthesized non-platinum metal compounds, exhibit potential antitumor activity; however, the antitumor mechanism is unclear. The current study investigated the mechanism by which β-diketone-cobalt complexes inhibit rat C6 glioma cell proliferation. It was found that β-diketone-cobalt complexes suppress rat C6 glioma cell viability in a dose-depende...

The photo-induced charge transfer in four series of Prussian blue (PB) analogues was studied from photoacoustic spectra. In cobalticyanides the observed signals were assigned to a metal-to-ligand charge transfer, which appears as a shoulder below 450 nm, and to d-d transitions for Co(II), Ni(II) and Cu(II) complex salts. No evidence of metal-to-metal charge transfer was observed for this series...

Pentanuclear cyanide-bridged clusters of the general formula {[M(tmphen)(2)](3)[M'(CN)(6)](2)} (tmphen = 3,4,7,8-tetramethyl-1,10-phenanthroline) have been under investigation in our laboratories for a number of years. These related molecules are conveniently prepared by a building block approach that involves the reaction of mononuclear {M(tmphen)(2)X(2)}(0/2+) species (M = Cr, Mn, Fe, Co, Ni,...

an approach to recycle precious metals of cathode materials from spent lithium cobalt oxide batteries by using organic citric acid and hydrogen peroxide has been studied in this paper. the effects of molar ratio, solid-liquid ratio, reaction time and temperature on leaching efficiency of cobalt were investigated respectively. meanwhile the leaching kinetics equation of cobalt was established, a...

Some macroglial cells of the O-2A lineage express glutamate receptor channels of the quisqualate/kainate type and take up extracellular cobalt when activated by glutamate agonists. These cells can be identified both in vitro and in situ following precipitation and intensification of the intracellular cobalt. We have used this technique to characterize these cells in the developing and adult rat...

A series of non-precious metal electrocatalysts, namely pyrolyzed carbon-supported cobalt-polypyrrole, Co-PPy-TsOH/C, are synthesized with various cobalt precursors, including cobalt acetate, cobalt nitrate, cobalt oxalate, and cobalt chloride. The catalytic performance towards oxygen reduction reaction (ORR) is comparatively investigated with electrochemical techniques of cyclic voltammogram, ...

The incorporation of cobalt into low molecular mass nitrile hydratase (L-NHase) of Rhodococcus rhodochrous J1 has been found to depend on the alpha-subunit exchange between cobalt-free L-NHase (apo-L-NHase lacking oxidized cysteine residues) and its cobalt-containing mediator (holo-NhlAE containing Cys-SO(2)(-) and Cys-SO(-) metal ligands), this novel mode of post-translational maturation havin...