نتایج جستجو برای: coagulation pathway

تعداد نتایج: 358621  

2005
Sorella Ilveskero Riitta Lassila Marja Mutanen Markku Heikinheimo

........................................................................................................................ 9 INTRODUCTION ............................................................................................................... 11 REVIEW OF THE LITERATURE ...................................................................................... 13 1. Platelets .....................

Journal: :Genetics and molecular research : GMR 2011
R F Zhou Y Liu Y X Wang W Mo M Yu

Tissue factor (coagulation factor III) is a cell surface receptor for coagulation factor VII/VIIa; it was initially recognized as an initiator of the extrinsic coagulation pathway. Recently, the zebrafish tissue factor gene (TF) has been cloned. Paralogs encode coagulation factors IIIa and IIIb; both show remarkable sequence identity to the human and mouse coagulation factor III gene. It ...

Journal: :Journal of Immunology 2023

Abstract The metabolism of macrophages plays a key role in their immune responses, but the mechanisms by which is regulated remain largely unknown. We show here that TGF-β induces unique phenotype and regulates glycolysis independently inflammatory cytokine production. Specifically, increased expression activity phosphofructokinase-1 liver type (PFKL) thus promoted during cell activation, yet p...

Journal: :Blood 1996
K Johnson L Aarden Y Choi E De Groot A Creasey

Acute inflammatory illnesses, including the sepsis syndrome, often include a component of coagulation. A human whole blood culture system was developed so that the relationship between coagulation activation and cytokine responses in the presence or absence of lipopolysaccharide (LPS) could be evaluated. In the absence of LPS stimulation, coagulation activation resulted in a novel pattern of cy...

2016
Isao Uchimura Makoto Kaibara Masayuki Nagasawa Yoshihito Hayashi

BACKGROUND Hypercoagulability in type 2 diabetes mellitus (T2DM) patients increases their risk of cardiovascular diseases. OBJECTIVE The aim of this work was to investigate the hypercoagulation mechanism in T2DM patients in terms of circulating tissue factor (TF). METHODS Whole blood coagulation tests by damped oscillation rheometry and dielectric blood coagulometry (DBCM) were performed. ...

Journal: :international journal of hematology-oncology and stem cell research 0
mehrdad payandeh medical biology research center, kermanshah university of medical sciences, kermanshah, iran mohammad erfan zare medical biology research center, kermanshah university of medical sciences, kermanshah, iran; studen atefeh nasir kansestani medical biology research center, kermanshah university of medical sciences, kermanshah, iran; studen kamran mansouri medical biology research center, kermanshah university of medical sciences, kermanshah, iran; departmant zohreh rahimi medical biology research center, kermanshah university of medical sciences, kermanshah, iran; departmant amir hossein hashemian department of biostatistics, faculty of public health, kermanshah university of medical sciences, kermanshah

introduction: normal homeostasis system has several inhibitor mechanisms in front of the amplifier’s natural clotting enzyme to prevent fibrin clots in the vessels. the main inhibitors of coagulation pathway are antithrombin (at), protein c and protein s. patients with hereditary deficiency of coagulation inhibitors are susceptible to venous thromboembolism (vte). one of the major clinical mani...

Journal: :فصلنامه علمی پژوهشی گیاهان دارویی 0
a qaderi m omidi a etminan a oladzad c ebrahimi mr dehghani mashkani

taxol is used to treatment of variety cancers including ovarian, breast, lung, head and neck carcinomas and the aids-related karposi’s carcinoma, and was originally obtained from bark of taxus brevifolia. however the amount of extracted taxol from taxus is extremely low and cannot be considered as a suitable commercial source and it has led to studies for finding new sources of taxol. in 1998, ...

Journal: :physiology and pharmacology 0
vahid khori golestan cardiovascular research center, golestan university of medical sciences, gorgan, iran samaneh naeimipour department of biology, faculty of basic science, azad university science & research center, tehran ali-mohammad alizadeh cancer research center, tehran university of medical sciences, tehran, iran mona pourabouk golestan cardiovascular research center, golestan university of medical sciences, gorgan, iran fakhri badaghabadi golestan cardiovascular research center, golestan university of medical sciences, gorgan, iran maryah rajaei golestan cardiovascular research center, golestan university of medical sciences, gorgan, iran

introduction: intranodal pathways of atrioventricular (av) node play a vital role in the delay of conduction time in response to various atrial inputs. the present study was aimed to determine the frequency-dependent electrophysiological properties of concealed slow pathway according to a functional model of isolated rabbit atrioventricular node preparation after fast pathway ablation. methods:...

Journal: :Archives of Medical Science 2021

Introduction The present study aimed to investigate the differences in proteomic expression between uncomplicated parapneumonic pleural effusion (UPPE) and complicated (CPPE). Material methods There were 10 patients with UPPE CPPE. These combined due complication of further divided into group A B. An LC-MS analysis was conducted extraction high-abundance proteins, proteins 1.5-fold or higher di...

Journal: :The Journal of clinical investigation 1985
G A Levy B S Schwartz L K Curtiss T S Edgington

The Shwartzman reaction is a classic biologic response in which the coagulation system is activated in vivo. Cellular initiation of the extrinsic coagulation protease cascade can be mediated by one or more limbs of the lymphoid response to diverse biological stimuli. The T cell-instructed monocyte and macrophage responses that have been implicated are mediated by a number of different cellular ...

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