نتایج جستجو برای: coagulation changes

تعداد نتایج: 914988  

2016
Duane Mortenson Torry Cobb AJ Sommers Anya Hill

Background: The numbers of individuals age 50 and over who maintain active lifestyles is growing. Many of these individuals travel to or live at, higher altitudes, to pursue outdoor activities or travel to higher altitudes for business. The use of anticoagulant therapy has continued to increase over the past two decades among individuals 50 and over. Warfarin is effective but requires a narrow ...

Journal: :The Journal of toxicological sciences 2009
Masahiro Mochizuki Hajime Abe Kei Wakabayashi Hiroyasu Yoshinaga Emi Okazaki Tsubasa Saito Mariko Fujita Hiroshi Edamoto Yuzo Asano

The effects of repeated administration of phenobarbital (PB) on blood coagulation time were examined using male Japanese white SPF rabbits, which are widely used for toxicological studies. PB was administered to the rabbits by oral gavage for 2 weeks, at dose levels of 0, 12.5, 25 and 50 mg/kg/day. Blood was collected on Days 8 and 14 after each day's dosing to perform blood coagulation examina...

Journal: :The Journal of trauma 2011
Daniel N Darlington Bijan S Kheirabadi Angel V Delgado Michael R Scherer Wenjun Z Martini Michael A Dubick

BACKGROUND As part of our overall interest in the mechanisms and treatment related to the development of the lethal triad of hypothermia, acidosis, and coagulopathy seen in trauma patients, the purpose of this study was to determine whether acidosis, inducible either by HCl infusion or hemorrhage/hypoventilation, leads to coagulopathy, and if correction of the acidosis will alleviate this coagu...

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