dermoid cyst is a tumor arises due to embryogenesis impairment. it accounts for less than 0.3 percent of all intracranial masses. a 35 years old man presented with a tonic clonic seizure without any significant past history of seizure. physical examination and imaging propounded epidermoid cyst as diagnosis. the patient had a craniotomy and cyst was totally removed. operative findings and histo...

Although the cause of sudden unexplained death in epilepsy patients (SUDEP) is unknown, evidence implicates respiratory compromise. Most cases occur while the patient is in bed and unsupervised. We investigated the efficacy of the Medpage bed seizure monitor to detect generalized tonic-clonic seizures. Patients with a history of tonic-clonic seizures were enrolled on a video-EEG unit. The MP5 d...

OBJECTIVE To assess the frequency, characteristics, and risk of injury during seizure attacks. DESIGN Questionnaire survey. SETTING Epilepsy out-patient clinic of the National Hospital for Neurology and Neurosurgery, Institute of Neurology, London. PATIENTS One hundred consecutive epileptic patients and their caretakers or relatives, who attended the hospital between 1 May and 30 June 200...

Objective(s): Phthalimide-based derivatives have anticonvulsant activity like as phenytoin by inhibition of sodium channel. In our previously research we mentioned about some phthalimide derivatives as potent anticonvulsant agents. Materials and Methods: Fourteen analogs of 2-substituted phthalimide pharmacophore were synthesized and then were evaluated for the anticonvulsant activities in pent...

Fahr's syndrome is a neuropsychiatric syndrome characterized by symmetrical and bilateral intracerebral calcifications located in the basal ganglia and usually associated with a phosphorus and calcium metabolism disorder. Clinical manifestations of Fahr's syndrome vary; it may start at different ages and have a variety of presentations. This article discusses rare presentation of Fahr's syndrom...

•7 of 9 patients with GGE reduced ≥ 50% their tonic-clonic seizure frequency on LCM.•All 7 patients remained seizure free for > 1 year, and 2 of them for > 5 years.•In 2 of the 9 patients, both with Juvenile Absence Epilepsy, absences aggravated.•One aggravation consisted on a myoclonia and absence status, in a patient with no history of myoclonia.•VEEG paralleled clinical improvement but didn'...

Nonunion of the humeral shaft in patients with antiepileptic drug associated metabolic bone disorder constitute a challenging surgical problem difficult to treat due to seizure activity, osteoporosis, and poor stabilization options. We report a case of nonunion of the humeral shaft in an antiepileptic drug patient with uncontrolled generalized tonic-clonic seizure activity successfully treated ...

A seven month old infant presented with excessive crying on handling following recovery from a generalized tonic clonic seizure. On examination he was noted to have swelling and tenderness over his left clavicle. There was no history of trauma. Chest radiograph disclosed undisplaced fracture of left clavicle at the junction of outer third and middle third. The fracture was attributed to the sei...

Myocardial infarction is diagnosed when blood levels of biomarkers are increased in the clinical setting of acute myocardial ischemia. Among the biomarkers, troponin I is the preferred biomarker indicative of myocardial necrosis. It is tissue specific for the heart. Myocardial infarction is rarely reported following seizure. We report a case of elevated troponin I in a patient after an episode ...