1. Eckert C, Gautier V, Arlet G. DNA sequence analysis of the genetic environment of blaCTX-M genes. J Antimicrob Chemother 2006; 57: 14–23. 2. Cantón R, Coque TM. The CTX-M b-lactamase pandemic. Curr Opin Microbiol 2006; 9: 466–75. 3. Partridge SR, Hall RM. In34, a complex In5 family class 1 integron containing orf513 and dfrA10. Antimicrob Agents Chemother 2003; 47: 342–9. 4. Valverde A, Cant...

In 200 sulfonamide-resistant Portuguese Salmonella isolates, 152 sul1, 74 sul2, and 14 sul3 genes were detected. Class 1 integrons were always associated with sul genes, including sul3 alone in some isolates. The sul3 gene has been identified in isolates from different sources and serotypes, which also carried a class 1 integron with aadA and dfrA gene cassettes.

Background: This study aimed to describe the association between age groups and antimicrobial susceptibility patterns, also integron presence in Escherichia coli and Klebsiella pneumoniae  isolates from Tabriz, Iran. Materials and methods: 140 isolates of E. coli and 150 isolates of K. pneumoniae, both comprising the same number of children and adult isolates were examined for susceptibil...

Conjugative transposons in Gram-negative bacteria have a significant role the dissemination of antibiotic-resistance-conferring genes between bacteria. This study aims to genomically characterize plasmids and conjugative carrying integrons clinical isolates Klebsiella pneumoniae. The genetic composition phenotypic assessment 50 multidrug-resistant K. pneumoniae from tertiary-care hospital (SQUH...

OBJECTIVES Vibrio cholerae O1 from a 2006 outbreak in Accra were commonly resistant to multiple antimicrobials and, in particular, to trimethoprim/sulfamethoxazole, drugs commonly used in the treatment of cholera. We sought to determine the genetic basis for trimethoprim/sulfamethoxazole resistance in outbreak isolates. METHODS Twenty-seven isolates from the outbreak were screened by PCR and ...

On a large plasmid of Acinetobacter johnsonii strain XBB1 from hospital sewage, blaPER-1 and ISCR1 were found in a complex Tn402-like integron carrying an arr3-aacA4 cassette array. The integron was truncated by the same 439-bp miniature inverted-repeat transposable element (MITE) at both ends. blaPER-1 and its complex surroundings might have been mobilized by the MITEst into an orf of unknown ...

OBJECTIVES We analysed the architecture and probable origin of a class 1 integron from cefotaxime-resistant Morganella morganii isolates. METHODS bla genes and class 1 integron elements were detected by PCR and DNA-DNA hybridization in a M. morganii strain isolated in 1996. PCR-mapping and sequencing of different fragments were carried out to determine the integron's architecture. RESULTS A...

1. Mazel D. Integrons: agents of bacterial evolution. Nat Rev Microbiol 2006; 4: 608–20. 2. Hansson K, Sundström L, Pelletier A et al. IntI2 integron integrase in Tn7. J Bacteriol 2002; 184: 1712–21. 3. Ahmed AM, Furuta K, Shimomura K et al. Genetic characterization of multidrug resistance in Shigella spp. from Japan. J Med Microbiol 2006; 55: 1685–91. 4. Dubois V, Parizano MP, Arpin C et al. H...