background: cutaneous leishmaniasis (cl) is a major health problem in many parts of iran, although diagnosis of cl especially in the endemic area is easy, but treatment and management of the disease is a global dilemma. diag-nosis of cl in non-endemic area is not as simple as in endemic foci. in this study, the status and the proportions of cl induced by leishmania major and l. tropica among cl...

A broad range of well-structured problems-embracing forms of diagnosis, catalog selection, and skeletal planning-are solved in “expert systems*’ by the method of heuristic classification. These programs have a characteristic inference structure that systematically relates data to a pre-enumerated set of solutions by abstraction, heuristic association, and refinement. In contrast with previous d...

We have studied the regulation of the K-Cl cotransporter KCC1 and its functional interaction with the Na-K-Cl cotransporter. K-Cl cotransporter activity was substantially activated in HEK-293 cells overexpressing KCC1 (KCC1-HEK) by hypotonic cell swelling, 50 mM external K, and pretreatment with N-ethylmaleimide (NEM). Bumetanide inhibited 86Rb efflux in KCC1-HEK cells after cell swelling [inhi...

The regulatory mechanisms of intracellular Cl- concentration ([Cl-]i) were investigated in the lateral superior olive (LSO) neurons of various developmental stages by taking advantage of gramicidin perforated patch recording mode, which enables neuronal [Cl-]i measurement. Responses to glycine changed from depolarization to hyperpolarization during the second week after birth, resulting from [C...

The maintenance of ion homeostasis requires adequate ion sensors. In leeches, 34 nephridial nerve cells (NNCs) monitor the Cl(-) concentration of the blood. After a blood meal, the Cl(-) concentration of leech blood triples and is gradually restored to its normal value within 48 h after feeding. As previously shown in voltage-clamp experiments, the Cl(-) sensitivity of the NNCs relies on a pers...

Of the total one-way chloride fluxes (approximately 1.4 meq/liter cell water X min) in steady state human polymorphonuclear leukocytes bathed in 148 mM Cl media, approximately 70% behaves as self-exchange mediated by a nonselective anion carrier that is not inhibited by stilbene disulfonates. Five properties of this carrier-mediated exchange were investigated: substrate saturation is seen with ...

In this paper, we show that a pointwise-symmetric isotonic closure function is uniquely determined by the pairs of sets it separates. We then show that when the closure function of the domain is isotonic and the closure function of the codomain is isotonic and pointwise-symmetric, functions which separate only those pairs of sets which are already separated are continuous, generalizing a result...

background: this study sought to assess symphyseal morphology in adolescents with different mandibular growth patterns (mgps) in order to see if a relation exists. materials and methods: in this study the symphyseal parameters (height, depth, and ratio) of normal subjects were compared with four groups with malocclusion (cl iii vertical, cl ii vertical, cl iii horizontal, and cl ii horizontal)....

In this paper, aggregation behaviors of aqueous solutions of short chain hydrophilic Ionic Liquids (ILs), 1 – allyl - 3 - methylimidazolium chloride ([Amim]Cl), 1 - ethyl - 3 - methylimidazolium chloride ([Emim]Cl), 1 - butyl - 3 - methylimidazolium chloride ([Bmim]Cl), 1 - butyl - 3 - methylimidazolium tetrafluoroborate ([Bmim]BF4) were investigated using conductivity and laser ...