Studies of circular DNA confined to nanofluidic channels are relevant both from a fundamental polymer-physics perspective and due to the importance of circular DNA molecules in vivo. We here observe the unfolding of DNA from the circular to linear configuration as a light-induced double strand break occurs, characterize the dynamics, and compare the equilibrium conformational statistics of line...

Mechanotransduction is required for a wide variety of biological functions. The aim of this study was to determine the effect of activation of a mechanosensitive Ca(2+) channel, present in human jejunal circular smooth muscle cells, on whole cell currents and on membrane potential. Currents were recorded using patch-clamp techniques, and perfusion of the bath (10 ml/min, 30 s) was used to mecha...

This paper makes an attempt to develop least squares lattice algorithms for the ARMA modeling of a linear, slowly time-varying, multichannel system employing scalar computations only. Using an equivalent scalar, periodic ARMA model and a circular delay operator, the signal set for each channel is defined in terms of circularly delayed input and output vectors corresponding to that channel. The ...

KATP channels, oligomers of 4 pore-forming Kir6.2 proteins and 4 sulfonylurea receptors (SUR), sense metabolism by monitoring both cytosolic ATP, which closes the channel by interacting with Kir6.2, and ADP, which opens it via SUR. SUR mutations that alter activation by ADP are a major cause of KATP channelopathies. We examined the mechanism of ADP activation by analysis of single-channel and m...

In this paper we analyze the temporal and spatial compression characteristics of retrodirective antenna systems wherein active phase conjugation (APC) is deployed. It is shown that under the active phase conjugation Hermitian channel matrix properties result and these lead to opportunities for both temporal and spatial signal compression. The effects of additive channel noise, as well as compre...

In this work channel coding and link adaptation in LTE are considered, which are important issues in modern digital communication systems. With channel coding, errors caused by distortion during transmission are detected and/or corrected. In LTE both convolutional and Turbo codes are used. The structure of convolutional codes in LTE is presented here. Turbo codes and internal contentionfree int...

The purpose of this paper is to investigate the use of combined spatial and temporal equalization, in particular for short training sequences. The motivation for combining spatial and temporal equalization is the existence of mul-tipath propagation and co-channel interference. Our main concern is to obtain good performance yet low complexity. We will suggest a low complexity algorithm utilizing...