Electronic cigarettes (e-cigarettes) are battery-powered devices that deliver a heated aerosol, which typically contains nicotine, flavorings, and other additives, to the user. The e-cigarette marketplace is rapidly evolving, but the long-term health effects of these products are not known. Carcinogens and toxins such as diacetyl, acetaldehyde, and other harmful chemicals have been documented i...

OBJECTIVE To determine the substance-use patterns of National Collegiate Athletic Association (NCAA) student-athletes for alcohol, amphetamines, anabolic steroids, cocaine/crack, ephedrine, marijuana/hashish, psychedelics/hallucinogens, and smokeless tobacco. DESIGN Self-reported, anonymous, retrospective survey. PARTICIPANTS Male and female student-athletes from 30 sports competing at 991 ...

Tobacco warning labels are important sources of risk information but research historically has been cigarette-centric. This qualitative study aimed to inform future direction and research on warnings for e-cigarettes. Between June and August 2016, we conducted interviews with 10 researchers with expertise in tobacco warning label research. Interviewees were registrants of a 2016 National Cancer...

Given the high rate of drug abuse in society, this study investigates how much its knowledge is available to secondary school students. Also evaluated perceived effect on their academic achievement subjects such as Computer science and allied subjects. A questionnaire was developed obtain respondents’ opinion with 304 responses analyzed for study. This research reveals that majority (97.4%) stu...

BACKGROUND Cannabis users are highly likely to also be tobacco cigarette smokers and a proportion of this comorbidity is attributable to shared genetic influences. Three large meta-analyses of genomewide association studies (GWAS) of tobacco smoking have identified multiple genomewide significant (p<5×10(-8)) single nucleotide polymorphisms (SNPs). We examine whether these SNPs are associated w...

OBJECTIVE The abuse potential of methylphenidate has been related to the drug's capacity to produce a rapid onset of blockade of the presynaptic dopamine transporter in the brain. An oral once-a-day osmotic controlled-release formulation of methylphenidate produces a more gradual rise in plasma methylphenidate concentration, compared with immediate-release methylphenidate. The authors hypothesi...

Methylphenidate is the most widely prescribed pharmacotherapeutic treatment of AD/HD in children and teens and has actions that are also involved in drug reward and reinforcement. Its clinical use has often raised concerns over the possibility that it could potentiate the risk for later drug-related problems. Animals exposed to methylphenidate during adolescence exhibit attenuated cocaine-induc...

BACKGROUND Substance abuse is one of the main health problems in Iran andawareness about its spread and procedure of spread in the society,particularly the susceptible society of students, is very important withregard to the population pyramid of Iran. METHODS This study was performed by cross-sectional method. The sampling sizewas 610 male students in pre-university grade by a probabilistic ...

In their article about drug use among teenage students in Ontario (page 451) Drs. Edward Adlaf and Frank Ivis present us with a warning. Their 1997 survey of students in grades 7, 9, 11 and 13 showed that cigarette smoking and alcohol use were continuing at high rates (reported by 27.6% and 59.6% of the sample respectively), that cannabis use had increased from 11.7% to 24.9% between 1991 and 1...