Although chronic obstructive pulmonary disease (COPD) is attributed predominantly to tobacco smoke, occupational exposures are also suspected risk factors for COPD. Estimating the proportion of COPD attributable to occupation is thus an important public health need. A randomly selected sample of 2,061 US residents aged 55-75 yrs completed telephone interviews covering respiratory health, genera...

Chronic obstructive pulmonary disease (COPD) exacerbations impair health. The present authors analysed participants in the Boston Early-Onset COPD Study for familial aggregation and propensity for COPD exacerbations. In the present study, two exacerbation outcomes, episodes of cough and phlegm, and frequent exacerbations were analysed with multivariable modelling and generalised estimating equa...

Chronic obstructive pulmonary disease (COPD) is a common and treatable in the general population, accounting for high morbidity mortality rates. In patients with severe COPD, hypoxemia main cause of complications such as hypertension (PH) right ventricle (RV) dysfunction. However, presence RV vascular structural functional changes may occur early stages even before significant or PH. Subclinica...

Chronic obstructive pulmonary disease (COPD) is associated with a high clinical and economic burden the fourth leading cause of death in United States. The management patients COPD aims to minimize control symptoms, prevent exacerbations, improve quality life. We provide an illustrated case study female patient typical progression describe diagnosis, assessment, strategy, referring evidence see...

There is considerable evidence that an increased oxidative burden occurs in the lungs of patients with chronic obstructive pulmonary disease (COPD) and this results in an imbalance between oxidants/antioxidants or oxidative stress, which may play a role in many of the processes involved in the pathogenesis of COPD. These include enhanced proteolytic activity, mucus hypersecretion and the enhanc...

Latent viral infection has been implicated in the pathophysiology of chronic obstructive pulmonary disease (COPD). Epstein-Barr virus (EBV) is known to be important in pulmonary fibrosis. The current authors hypothesised that EBV is associated with the pathogenesis of COPD. Sputum samples were collected from patients both during exacerbations of COPD and when stable. A control group of smokers ...

acute exacerbations of COPD: bringing pressure to bear. Age Ageing 2006; 35: 1–2. 3. Balami JS, Packham SM, Gosney MA. Non-invasive ventilation (NIV) for respiratory failure due to acute exacerbations of chronic obstructive pulmonary disease (COPD) in older patients. Age Ageing 2006; 35: 75–8. 4. National Collaborating Centre for Chronic Conditions. Chronic obstructive pulmonary disease in adul...

The occupational contribution to chronic obstructive pulmonary disease (COPD) has yet to be put in a global perspective. In the present study, an ecological approach to this question was used, analysing group-level data from 90 sex-specific strata from 45 sites of the Burden of Obstructive Lung Disease study, the Latin American Project for the Investigation of Obstructive Lung Disease and the E...

introduction: chronic obstructive pulmonary disease (copd) patients are at increased risk of sleep-disorders. the concomitant occurrence of copd and obstructive sleep apnea hypopnea syndrome (osahs) is named overlap syndrome. this study aimed to evaluate the severity of osahs in overlap syndrome patients.materials & methods: this cross-sectional study was conducted on adult patients with forced...