Gastric mucosal phospholipids, and in particular those of the surface layer, play an important part in mucosal barrier function. This study examined whether the phospholipid composition of the full thickness gastric mucosa is changed in peptic ulcer disease and gastritis. The phospholipid composition of gastric mucosa from endoscopic biopsy specimens in 28 subjects (eight healthy controls, 12 p...

Helicobacter pylori status, gastric histology, and 24 hour acidity were studied in 35 gastritis patients, 21 duodenal ulcer patients, and 14 subjects with normal gastric mucosa. H pylori was identified in 21 of 35 patients with chronic active gastritis and in 19 of 21 duodenal ulcer patients, but in none of those with normal gastric mucosa. Mean scores of activity of gastritis were similar in H...

CONTEXT Although Helicobacter pylori infection is prevalent in our country, there are few studies evaluating the associated histological abnormalities in children. OBJECTIVE To evaluate the histological features of the gastric mucosa in children and adolescents with Helicobacter pylori gastritis. METHODS One hundred and thirty two gastric biopsies from 22 symptomatic patients infected with ...

Prospective investigation has been undertaken with the aim to study the frequency, location and age and sex distribution of various histological types of benign gastric epithelial polyps. Histological type--adenomatous, hyperplastic and fundic gland polyps--was diagnosed on the basis of at least three histological samples taken from the polyp. Biopsy samples were also taken from the antrum and ...

BACKGROUND Gastric carcinogenesis is a multifactorial, multistep process, in which chronic inflammation plays a major role. AIMS In order to ascertain whether free radical mediated oxidative DNA damage is involved in such a process, concentrations of 8-hydroxydeoxyguanosine (8OHdG), a mutagenic/carcinogenic adduct, and thiobarbituric acid reactive substances (TBARS), as an indirect measure of...

Helicobacter pylori ( H. Pylori ) is the best example of implication chronical infection in carcinogenesis. The World Health Organization recognized it as a class I carcinogen since triggers progression premalignant gastric lesions. aim this study to define prevalence infection, related risk factors, and explore histological features chronic gastritis. This retrospective 248 specimens, examinat...

aim: the objective of this study was to evaluate the time trend of helicobacter pylori ( h. pylori ) prevalence and presence of intestinal metaplasia over the period of 7 years in gastritis iranian patients. background: h. pylori are the major causal factor in chronic gastritis. its acquisition leads to a chronic, usually lifelong, inflammation of the gastric mucosa, which may gradually progres...

Chronic gastritis is defined as the presence of chronic mucosal inflammatory changes leading eventually to mucosal atrophy and epithelial metaplasia. It is notable for distinct causal subgroups and for patterns of histological alterations that vary in different parts of the world. By far the most important aetiological association is chronic infection by the bacillus Helicobacter pylori (Hp). T...

AIM To explore the correlation between serum vitamin B12 level and peripheral neuropathy in patients with chronic atrophic gastritis (CAG). METHODS A total of 593 patients diagnosed with chronic gastritis by gastroscopy and pathological examination from September 2013 to September 2016 were selected for this study. The age of these patients ranged within 18- to 75-years-old. Blood pressure, h...

CONTEXT Gastric cancer is one of the top list of cancer types that most leads to death in Brazil and worldwide. Helicobacter pylori(H. pylori) is a class I carcinogen and infect almost 90% of chronic gastritis patients. Some genotypes confer different virulent potential to H. pylori and can increase the risk of gastritis development. Methylation of CpG islands can inactivate tumor suppressor ge...