A series of 474 mixed cases of glaucoma was assessed to determine whether there were any genetic differences between different types of glaucoma. A careful distinction was made between chronic open angle glaucoma (COAG), acute and chronic angle closure glaucoma, ocular hypertension, low tension glaucoma, patients with large cup disc ratios, and various types of secondary glaucoma including pseu...

PURPOSE The membrane frizzled-related protein (MFRP) has been proposed as a probable candidate gene for extreme hyperopia and nanophthalmos, which are factors for angle-closure glaucoma. The purpose of our study was to investigate whether there are significant associations between angle-closure glaucoma and sequence variants in the MFRP gene reported previously in Taiwanese subjects. METHODS ...

A mild anterior chamber aqueous flare and cellular response are common findings in acute angle-closure glaucoma. Chandler and Grant (I965) have noted that "discovery of a great many cells in the aqueous is perfectly consistent with the diagnosis of acute angle-closure glaucoma". We have recently seen two patients who had developed hypopyon during the course of their attacks of acute angle-closu...

The Guidelines Project, an initiative of the Brazilian Medical Association, aims to combine information from the medical field in order to standardize procedures to assist the reasoning and decision-making of doctors. The information provided through this project must be assessed and criticized by the physician responsible for the conduct that will be adopted, depending on the conditions and th...

Glaucoma is undergoing a paradigm shift and transitioning from merely disease staging to evidence-based risk assessment of in the individual patient.Initially introduced for ocular hypertensive patients, risk assessment calculators are now being developed for patients with established glaucoma.

We present the handbag contribution to Wide Angle Compton Scattering (WACS) at moderately large momentum transfer obtained with a proton distribution amplitude close to the asymptotic form. In comparison it is found to be significantly larger than results from the hard scattering (pQCD) approach.

PURPOSE To investigate the association of PLEKHA7 and COL11A1 with primary angle closure glaucoma, as well as acute and chronic subphenotype, in a Han Chinese population. METHODS A total of 984 cases, including 606 primary angle closure glaucoma (PACG) and 378 primary angle closure (PAC), and 922 normal controls were recruited. Twelve single nucleotide polymorphisms (SNPs) (rs1676486, rs37538...