Emerging roles for epigenetic modifications and chromatin remodeling in the nervous system provide the focal point for this issue’s Neurobiology Select. Recent evidence shows that changes in chromatin structure are critical to the reconsolidation of fear memories. Other new papers characterize the regulation of neural stem cells by histone acetylation and establish roles for epigenetic modifica...

E nzymes that use energy gained by ATP-hydrolysis to alter nucleosomes, the building blocks of chromatin, are involved in all processes occurring on DNA (1, 2). These ATP-dependent chromatin remodeling factors regulate access to DNA either by moving nucleosomes away from a transcription factor binding site or into such a site, occluding further access (1, 2). All known ATP-dependent nucleosome ...

Preimplantation development of the mammalian embryo consists of stages that include formation of the <span style="font-variant: normal; font-style: normal; font-family: ArialM...