PATIENT Male, 73 FINAL DIAGNOSIS: Sacrococcygeal chordoma • SYMPTOMS Coccycodynia • sacral pain MEDICATION - Clinical Procedure: - Specialty: Surgery Objective: Rare disease. BACKGROUND Sacrococcygeal chordomas are rare and difficult to diagnose tumors. CASE REPORT A 73-year-old man in the last 6 months felt a pain in and around the coccyx when sitting and especially when rising from th...

Background Chordomas must be considered among the differential diagnoses for extradural spinal tumors, especially involving the clival or sacrococcygeal regions. They are often locally invasive and destructive to the osseous structures from which they arise, but rarely extend intradurally. Here, we report a unique chordoma that was intradural and spanned nearly four subaxial cervical vertebral ...

Chordoma is a rare, slow-growing malignant tumor arising from notochordal remnants. A retrospective review of patient records at two major referral centers was undertaken to assess the incidence, location, and prognostic factors of metastatic disease from chordoma. 219 patients with chordoma (1962-2009) were identified. 39 patients (17.8%) developed metastatic disease, most frequently to lung (...

The current report presents a case of a 78-year-old male with sacral chordoma, showing an aggressive clinical course. The patient underwent sacral resection, however, nine months later, multiple metastases were detected by magnetic resonance imaging. The metastases progressed rapidly and 15 months following surgery the patient succumbed to respiratory dysfunction. An autopsy revealed multiple m...

Chordomas are low-grade, locally invasive, frequently recurring, malignant bone tumor with poor prognosis. Cervical chordoma in adults is rare and often missed when patients present cervical radiculopathy. They can mimic other tumors and, hence require histologic distinction for prognostic risk stratification optimal treatment. We a 61-year-old male chronic neck pain sensory neuropathy bilatera...

Chordomas are rare tumors of notochordal tissue remnants and most frequently affect the sacrum and skull base. We report a case of a 58-year-old woman having cervical chordoma causing related symptoms for 5 years. MRI showed a dumbbell-shape mass with heterogeneous enhancement at C2 and C3 on postcontrast images, mimicking neurogenic tumor. Chordoma should be included in the differential diagno...

Chordoid meningioma is an uncommon histopathological variant of meningioma with a peculiar chordoma-like appearance. Its association with systemic inflammatory disorder linked to Castleman's syndrome was confirmed in the majority of young patients, however such a relationship in adults remains enigmatic. We report two cases of chordoid meningiomas in adult patients without manifestation of Cast...

UNLABELLED INTRODUCTION Clival chordomas present with headache, commonly VI cranial nerve palsy or sometimes with lower cranial nerve involvement. Very rarely, they present with cerebrospinal fluid rhinorrhoea due to an underlying chordoma-induced skull base erosion. CASE PRESENTATION A 60-year old Caucasian woman presented with meningitis secondary to cerebrospinal fluid rhinorrhoea. At f...

Chordoma is a rare malignant axial tumour that develops from embryonic remnants of the notochord. Surgery and irradiation are the standard initial treatment. However, local recurrence is frequent and cytotoxic chemotherapy is inefficient. Transient activity of imatinib, a platelet-derived growth factor receptor inhibitor, was described in a phase II study. Activity of epidermal growth factor re...