Cardiovascular diseases, as coronary heart disease, failure, and hypertension are the first leading cause of death in United States third globally. CETP is a glycoprotein excreted mainly from liver found plasma. Normal plasma concentration 1-4 µg/ml, while ratio increased 70-80% dyslipidemic patients. There growing need for new inhibitors which encourages us to conduct this research. In work, s...

Lymph chylomicrons labeled with 14C-cholesterol and plasma very low and intermediate density lipoproteins (d less than 1.019) labeled with 3H-cholesterol were injected simultaneously into recipient cholesterol-fed rabbits. The cholesteryl ester of chylomicron origin (14C) found in the tissues 1 to 4 hours after the injection is the sum of both direct and indirect uptake of chylomicron cholester...