background: chlorhexidine (chx) as a gold standard chemical agent appears to be the most effective antimicrobial agent for reduction of both plaque and gingivitis. the aim of this study was to compare the efficacy of two concentrations of digluconate chlorhexidine (chx) solutions (0.12% and 0.20%) on gingival indices and the level of dental staining during 14 days. materials and methods: in thi...

BACKGROUND This study presents a comparative investigation of the antimicrobial efficacy of the antiseptics PVP-iodine, triclosan, chlorhexidine, octenidine and polyhexanide used for pre-surgical antisepsis and antiseptic treatment of skin, wounds and mucous membranes based on internationally accepted standards. METHODS MICs and MBCs were determined in accordance with DIN 58940-7 and 58940-8 ...

IMPORTANCE Acanthamoeba keratitis is a debilitating eye disease that requires effective topical drug therapy. Currently, there is no standard in vitro test to evaluate anti-Acanthamoeba drugs. OBJECTIVE To develop a practical in vitro complete-kill assay to assess anti-Acanthamoeba drugs. DESIGN AND SETTING Isolates of Acanthamoeba strains (n = 15) evaluated in a clinical laboratory. An in ...

We read with great interest the recent article in CHEST (August 2009) by Pobo et al 1 concerning dental brushing for preventing ventilator-associated pneumonia (VAP). Since dental plaque can serve as a bacterial reservoir 2 that may cause VAP, oral care regimens that remove dental plaque could reduce the incidence of VAP. 3 Toothbrushes are generally regarded as the best tools for plaque remova...