This study investigated the antifungal effects of low-molecular-weight chitosan solution on Candida albicans in denture stomatitis in comparison with nystatin suspension. This randomized, sing-leblind clinical trial included 40 patients diagnosed with denture stomatitis. Patients were divided into two groups, wherein one was treated with chitosan and the other with nystatin for 2 weeks. Changes...

Two liquids are separated by a nanoporous membrane and one liquid is made to flow into the other, causing nanoparticles to be formed at the exits of the nanopores. In particular, we report the generation of nanoparticles of the biodegradable polysaccharide polymer chitosan by placing the chitosan in a low pH aqueous solution that is flowed into a high pH aqueous solution. The size of the nanopa...

objectives: ctxb (cholera toxin b subunit) contributes to a vaccine's efficacy by stimulating production of the anti-ctxb antibody. various attempts have been made to increase production of this antibody. chitosan is a mucoadhesive polysaccharide that has tremendous potential for oral vaccine delivery in terms of its exclusive features that include biocompatibility, biodegradability, high charg...

Hydroxyapatite (HAP; Ca10(PO4)6(OH)2) and whitlockite (WH; Ca18Mg2(HPO4)2(PO4)12) are widely utilized in bone repair because they are the main components of hard tissues such as bones and teeth. In this paper, we synthesized HAP and WH hollow microspheres by using creatine phosphate disodium salt as an organic phosphorus source in aqueous solution through microwave-assisted hydrothermal method....

This research evaluated the importance of the adsorption properties of chitosan a chitosan/zeolite conjugate film for the removal of Cr(VI) ions from solutions in the 5-260 mg/L concentration range, when the pH was adjusted to 4.0 and 6.0. The uptake capacities of the films formed by chitosan and by the chitosan/zeolite conjugate were calculated by mass balance. The equilibrium isotherms were f...

Oil-chitosan composite spheres were synthesized by encapsulation of sunflower seed oil in chitosan droplets, dropping into NaOH solution and in situ solidification. Hydrophilic materials (i.e., iron oxide nanoparticles) and lipophilic materials (i.e., rhodamine B or epirubicin) could be encapsulated simultaneously in the spheres in a one step process. The diameters of the prepared spheres were ...

The present work focused on the preparation and morphological characterization of chitosan-based nanofiber membranes, aiming at applications in medical and pharmacological areas. Membranes with nanofiber diameters ranging from 50 – 300 nm were prepared from polymer solutions through the electrospinning process. To stabilize the process, it was necessary to use poly(ethylene oxide) (PEO), which ...

background :gelatin and chitosan are known as biodegradable and biocompatible biopolymers.these biopolymers have recently receivedincreasingly more attention for tissueengineering.the aim of this study was to evaluate the toxicity effects of gelatin-chitosan film on bone marrow stromal cell(bmscs) culture in rat.                                                  materials & methods: first, gelat...

objective(s): nanoparticles (nps) are known for their specific accumulation in the inflamed tissues of the colon and thus allow a selective delivery to the site of inflammation with minimum adverse effects. the main objective of this work is to attain mesalamine loaded chitosan nanoparticles as a carrier for oral delivery. methods: in this study, mesalamine loaded chitosan nanoparticles were pr...

We report a simple method to produce stable chitosan derivative nanofibers via electrospinning. A chitosan solution with lactate salt was electrospun to produce nanofibers, followed by thermal treatment to enhance fiber stability. Chemical and morphological analyses demonstrated that the resulting nanofibers were crosslinked via amidation between chitosan and lactate salt. These fibers exhibite...