In this study we evaluated the effect of chitosan nanoparticles on the acid tolerance response (ATR) of adhered Streptococcus mutans. An ATR was induced by exposing S. mutans to pH 5.5 for 2 h and confirmed by exposing the acid-adapted cells to pH 3.5 for 30 min, with the majority of cells appearing viable according to the LIVE/DEAD® technique. However, when chitosan nanoparticles were present ...

The objective of this study was to prepare a suitable formulation for dermal delivery of diflucortolone valerate (DFV) that would maintain the localization in skin layers without any penetration and to optimize efficiency of DFV. Drug-loaded lecithin/chitosan nanoparticles with high entrapment efficiency (86.8%), were successfully prepared by ionic interaction technique. Sustained release of DF...

an innovative method based on the membrane bioreactor (mbr) technology was developed as a potential remedy for the water shortage. mbrs attracted much attention in the field of wastewater treatment and reuse. it is reported from many researchers that membrane bioreactor technology is feasible and an efficient method for the treatment of wastewater. however, mbrs are faced to membrane fouling whic...

the purpose of the present study was to develop glipizide controlled release nanoparticles using alginate and chitosan thorough ionotropic controlled gelation method. glipizide is a frequently prescribed second generation sulfonylurea which lowers the blood glucose in type-two diabetics. quick absorption of the drug from the gastrointestinal tract along with short half- life of elimination make...

background and objectives: mortality is highly variable within population of cultured fish due to virulent bacteria causing fish septicemia. the use of nano-silver marine fungal chitosan as antibiotic synergisers could be an alternative in the treatment of sepsis fish pathogens. materials and methods: different bulk chitosan solutions were prepared from the mycelia of four marine fungi ( asperg...

Absorption is a common technology used for water and wastewater treatment since it is often fast and efficient, while costly at the same time. Therefore, the development of low-cost and efficient adsorbents has led to the rapid growth of research interest in this regard. Chitosan is a natural polyaminosaccharide with effective adsorption properties, which is applied to remove various pollutants...

Since maleic acid is capable of specially dissolving Chitosan, in this research the method of producing water lubricant nanoparticles in Chitosan solution, based on maleic acid has been studied. The resulting nanoparticles have a remarkable contact surface with the ordinary Chitosan form in absorbing metal ions, proteins and fat existing in Whey. After providing the 0.02, 0.03, 0.05 gr. density...

BACKGROUND AND OBJECTIVE As a prospective vaccine carrier, nanoparticles can protect antigens from degradation and enhance immune response. This study prepared nanovaccines with MAGE-3-derived CD4+-CD8+T cell epitope peptides, and investigated its character and antitumor effects on transplanted gastric cancer in mice. METHODS We adopted the self-assembly method to prepare peptide/chitosan con...

BACKGROUND Schistosomiasis is one of the most important neglected tropical diseases and an effective control is unlikely in the absence of improved sanitation and vaccination. A new approach of oral vaccination with alginate coated chitosan nanoparticles appears interesting because their great stability and the ease of target accessibility, besides of chitosan and alginate immunostimulatory pro...