Polymerase chain reactions (PCR), thermally activated chemical reactions which are widely used for nucleic acid amplification, have recently received much attention in microelectromechanical systems and micro total analysis systems because a wide variety of DNA/RNA molecules can be enriched by PCR for further analyses. In the present work, a droplet-based micro oscillating-flow PCR chip was des...

Materials such as waste tire chips were widely used to improve the strength of soil. The objective of this study is to discuss the residual strength or steady-state behavior of sand-waste tire chip mixtures. A series of undrained monotonic triaxial compression tests were conducted on reconstituted saturated specimens of sand and sand-tire chip mixtures with variation in the tire-chip contents f...

the aim of this study is experimental assay of sensitivity and stability of a bimetallic silver/gold spr sensor chip. this chip utilizes the sensitivity of the silver and the stability of the gold. moreover, the silver layer (instead of usual cr or ti layer) was used as an adhesive intermediate layer between the gold layer and the glass substrate. the optimization of the gold/silver thickness u...

Nowadays, faults and failures are increasing especially in complex systems such as Network-on-Chip (NoC) based Systems-on-a-Chip due to the increasing susceptibility and decreasing feature sizes. On the other hand, fault-tolerant routing algorithms have an evident effect on tolerating permanent faults and improving the reliability of a Network-on-Chip based system. This paper presents reliabili...

Axons are long, slender processes extending from the cell bodies of neurons and play diverse and crucial roles in the development and function of nervous systems. Here, we describe the development of a chip device that can be used to produce large quantities of axons for proteomic and RNA analyses. On the chip surface, bundles of axons of rat hippocampal neurons in culture are guided to grow in...

FACT (facilitates chromatin transcription) is a chromatin-reorganizing complex that swaps nucleosomes around the RNA polymerase during transcription elongation and has a role in replication that is not fully understood yet. Here we show that recombination factors are required for the survival of yeast FACT mutants, consistent with an accumulation of DNA breaks that we detected by Rad52 foci and...

objectives: human immunodeficiency virus type 1 is the causative agent of acquired immunodeficiency syndrome “aids” in human and demonstration of hiv-1 genome in samples is accepted as evidence of infection. transmission of infection during window period in blood transfusion settings is a world wide concern. also there is a need for a rapid, sensitive and accurate technique to detect hiv-1 infe...

Forensic Short Tandem Repeat (STR) genotyping is almost exclusively performed by capillary electrophoresis (CE) in specialized laboratories. As an alternative to CE, and enable miniaturized lab-on-a-chip STR profiling, we developed the QueSTR probes, a hybridization-based assay that relies on recognition cleavage of RNA:DNA duplex RNase H2 enzyme. For each allele be genotyped, matching DNA prob...

Wireless network on chip (WiNoC) is one of the promising on-chip interconnection networks for on-chip system architectures. In addition to wired links, these architectures also use wireless links. Using these wireless links makes packets reach destination nodes faster and with less power consumption. These wireless links are provided by wireless interfaces in wireless routers. The WiNoC archite...