A 63-year-old woman suffering from progressive systemic sclerosis for about 20 years disclosed symptoms of liver disease within the last three years. Diagnosis of biliary cirrhosis was established on the basis of clinical picture, pathological examination of the hepatic tissue sample, immunological tests, and x-ray studies. Association of systemic sclerosis with primary biliary cirrhosis is...

Indian childhood cirrhosis (ICC), a disease considered to have been endemic in and unique to India has now been documented in children of non-Indian origin from other countries. More recently available findings from a large multicentre study sponsored by the Indian Council of Medical Research (ICMR) have dispelled some of the generally accepted notions and have established several new facts on ...

The biliary tract is normally sterile, but bile-tolerant bacteria are frequently isolated from patients with cholecystitis. Since the identification of about 25 Helicobacter species, some of which may grow in bile, studies have addressed the role of these organisms in primary biliary cirrhosis, primary sclerosing cholangitis, and cholelithiasis. Most of these bacteria show the presence of Helic...

how to cite this article: schulz a, kohlschütter a. ncl disorders: frequent causes of childhood dementia. iran j child neurol. 2013 winter;7(1):1-8. abstract dementia in children or young adults is most frequently caused by neuronal ceroidlipofuscinoses (ncl), a group of incurable lysosomal storage disorders linked by the accumulation of a characteristic intracellular storage material and progr...

life traumatic experiences are major health problems in different communities. early trauma exposures such as physical and sexual abuse, and midlife traumatic events like exposing to disasters are predisposing and precipitating risk factors for many psychiatric disorders, although many people facing to trauma may not show any problematic symptoms and are quite resilient. neuropsychiatric eviden...

results the allele and genotype distributions of pnpla3 rs738409 and rs2281135 were not significantly different between the chb and lc groups. after segregation on the basis of sex, no significant correlation between pnpla3 (rs738409 and rs2281135) genotypes/alleles and liver cirrhosis was detected. moreover, none of the haplotypes in pnpla3 (rs738409 and rs2281135) was found to be statisticall...

background hepatitis b virus (hbv) is among the leading causes of liver cirrhosis worldwide. predictors of cirrhosis in iranian chronic hepatitis b (chb) patients are yet to be clearly identified. objectives evaluating the predictive factors of liver cirrhosis in chb. patients and methods a longitudinal study was conducted during 1995 - 2014 on all chb patients who were referred to tehran hepat...

While the number of computers in the classroom continues to increase and tremendous support for technology integration exists in government, business, and academia, a major discrepancy exists between the level of technology use that is expected from the educators and the actual use and integration of technology in the classroom. However, effective technology integration in early childhood educa...

The liver is involved in the synthesis and metabolism of many kinds of hormones, various abnormalities hormone levels are found in advanced liver disease. For example the liver is, extremely sensitive to changes in insulin or glucagon levels. The liver is the primary organ of iron storage is frequently involved, diabetes is common in patients with iron overload and may be seen in cirrhosis. Chr...