A four month old male infant born with a birth weight of 2.5 kg presented with chickenpox. On examination, he weighed 11 kg and had cushingoid features. His blood pressure was normal and had multiple papulovesicular lesions characteristic of chickenpox. The child had to be treated with oral acyclovir in view of cushingoid features. At fifteen days of life, a private practitioner had prescribed ...

The varicella-zoster virus (VZV) causes two diseases: varicella (‘chickenpox’) and herpes zoster (‘shingles’). VZV vaccination of children reduces exposure to chickenpox in the population and it has been hypothesized that this could increase the prevalence of shingles. This ‘exogenous boosting’ effect of VZV raises an important equity concern: introducing a vaccination program could advance the...

CASE REPORT A 34-year-old male patient developed acute retinal necrosis in his left eye about three weeks after the onset of chickenpox. Systemic antiviral treatment with intravenous acyclovir (10 mg/kg/8 hours) and systemic corticosteroids (1 mg/kg/day) controlled the retinitis and the patient suffered no loss of visual acuity. DISCUSSION Acute retinal necrosis is an unusual complication of ...

The aim of the study . Determination immune response mediators in patients with infection caused by Varicella Zoster virus various clinical and laboratory parameters. Materials methods. VZV DNA polymerase reaction method. blood content proinflammatory was assessed using ELISA method monoclonal antibodies (Protein contour, Petersburg). Research result. In INF- α , γ CD-8+ significantly lower tha...

of symptoms, and the late onset ofthe vesicular rash. As a result of our experience in this case we recommend that varicella zoster antibodies should be measured in all patients receiving methotrexate and, if the result is negative, patients should be advised to seek medical attention when there is contact with chickenpox so that passive immunisation with varicella zos-ter immunoglobulins can b...

During the first quarter of 1998, the Texas Department of Health and the Iowa Department of Public Health notified CDC of three fatal cases of varicella (chickenpox) that occurred in children during 1997. All three children were unvaccinated. Two children contracted chickenpox from unvaccinated siblings, and the mode of exposure was unknown for the third. This report summarizes these cases and ...

Group A beta-hemolytic streptococcus and Staphylococcus aureus are the 2 most common pathogens implicated in secondary invasive bacterial disease after varicella. We describe a 3-month-old male infant from British Columbia, Canada, who presented on day 5 of varicella skin rash with fever, seizures, lethargy, and evidence of intracranial hypertension. A prominent subdural empyema was documented,...