background & aim: glioblastoma multiforme (gbm), the highest grade glioma (grade iv), is the most malignant form of astrocytoma in adults. this study aimed at evaluating the relationship between demographic, clinical and medical factors with gbm outcome. methods & materials/patients: through a cross-sectional design, 58 patients with newly diagnosed gbm were studied from 1999 to 2015 in guilan ...

studies on biomedical applications of nanoparticles are growing with a rapid pace. in medicine, nanoparticles may be the solution for multi-drug-resistance which is still a major drawback in chemotherapy of cancer. in the present study, we investigated the potential cytotoxic effect of silver nanoparticles (ag nps) and silver ions (ag+) in both parent and tamoxifen-resistant t47d cells in prese...

purpose : to report the outcome of a case of primary conjunctival rhabdomyosarcoma treated by surgical excision combined with chemotherapy case report : a 4-year-old boy presented with a visible recurrence of conjunctival mass in the left eye. the orbital magnetic resonance imaging (mri) showed the lesion was confined to the conjunctiva without orbital infiltration. histology and immunophenotyp...

conclusions atypical irregular tumors should be considered as sos when the patient has received oxaliplatin-based chemotherapy. a qualitative imaging modality diagnosis, such as with diffusion-weighted mri, is superior to a morphological diagnosis in focal sos. this imaging modality can prevent unnecessary operations. case presentation a 40-year-old woman with rectal cancer underwent high anter...

doxorubicin, used in pediatric chemotherapy regimens, has cardiotoxic effects. dexrazoxane is co-administrated with doxorubicin to prevent its cardiotoxicity. here we have explored some alternative food or drugs to be used in absence of dexrazoxane since it’s not readily available in iran at this time. keywords: pediatric, chemotherapy, doxorubicin, cardiotoxicity, dexrazoxane, iran.

objective: to report a case of long-term disease free and successful pregnancy after fertility sparing staging surgery with adjuvant chemotherapy in a 46,xy gonadal dysgenetic with malignant germ cell tumor. materials and methods: a case report from a university hospital about a 19-year-old female with 46,xy karyotype ( swyer syndrome). the patient underwent bilateral gonadectomy and staging wi...

evidence acquisition medline, pubmed, ovid and embase were used to search for clinical studies comparing with or without prophylactic use of lamivudine for hbv reactivation in breast cancer patients receiving chemotherapy. outcomes of interest were the rate of hbv reactivation, incidence of hepatitis and incidence of hepatitis attributable to hbv reactivation, severity of hepatitis and severity...

conclusions compared to supine position, semi-fowler’s position is more effective in relieving chemotherapy-induced nausea and vomiting. results the severity, duration, and frequency of nausea and the severity and frequency of vomiting episodes in the control group differed significantly across the nine measurement time-points (p < 0.001). in the experimental group, the severity (p = 0.254) and...

background : the purposes of this study were to examine the impact of chemotherapy treatment on jordanian cancer patients’ fatigue and to correlate their fatigue with selected sociodemographic variables at the beginning of treatment and after four weeks of treatment. methods : this was a single group quasi-experimental correlational design study that enrolled 43 patients diagnosed with cancer w...