The end-use application of most macromolecules is determined not only by their chemical identity but also, and sometimes more importantly, by the distributions and sequences of key physical and physicochemical parameters. The ability to determine these distributions is gained through separation science, by enlisting the aid of a large number of separation methods in combination with spectroscop...

The strand separation problem is that of calculating the probability of separation of each base pair in the DNA sequence under speci ed physical and chemical conditions. A computational method that performs an approximate statistical mechanical analysis of this phenomenon has previously been developed and shown to be accurate when compared

In spite of the efforts in increasing the analytical control on herbal medicines, difficulties in the standardization of their components and the absence of a thorough characterization of the chemical composition still persist and constitute obstacles to the safe therapeutic use of these substances. The public consider these products inoffensive and uses them intensively or extensively, includi...

Mixing and transport in turbulent flows-which have strong local concentration fluctuations-are essential in many natural and industrial systems including reactions in chemical mixers, combustion in engines and burners, droplet formation in warm clouds, and biological odor detection and chemotaxis. Local concentration fluctuations, in turn, are intimately tied to the problem of the separation of...

This work aims at the development of a dynamic model for the mathematical description of facilitated transport separation processes carried out in membrane contactors where mass transport phenomena are coupled with chemical reactions. A general model that takes into account the description of all possible mass transport steps and interfacial chemical reactions is initially presented, allowing i...

Separation of different domestic wastewater streams and targeted on-site treatment for resource recovery has been recognized as one of the most promising sanitation concepts to re-establish the balance in carbon, nutrient and water cycles. In this study a model was developed based on literature data to compare energy and water balance, nutrient recovery, chemical use, effluent quality and land ...

Cell and microparticle separation in microfluidic systems has recently gained significant attention in sample preparations for biological and chemical studies. Microfluidic separation is typically achieved by applying differential forces on the target particles to guide them into different paths. This paper reviews basic concepts and novel designs of such microfluidic separators with emphasis o...

Typical task in process design is to determine the configuration of a separation sequence. When dealing with multicomponent mixtures, the number of possible separation methods, their combinations and process structures to be screened is huge as well as the work involved. The method used, case-based reasoning (CBR), uses existing design cases stored in the database for solving new separation pro...