نتایج جستجو برای: chemical safety

تعداد نتایج: 632559  

Journal: :Journal of computer-aided molecular design 2005
Dmitry Filimonov Vladimir Poroikov

Both society and industry are interested in increasing the safety of pharmaceuticals. Potentially dangerous compounds could be filtered out at early stages of R&D by computer prediction of biological activity and ADMET characteristics. Accuracy of such predictions strongly depends on the quality & quantity of information contained in a training set. Suggestion that some relevant chemical inform...

Journal: :Journal of computer-aided molecular design 2005
Jean-Loup Faulon W. Michael Brown Shawn Martin

Physical, chemical and biological properties are the ultimate information of interest for chemical compounds. Molecular descriptors that map structural information to activities and properties are obvious candidates for information sharing. In this paper, we consider the feasibility of using molecular descriptors to safely exchange chemical information in such a way that the original chemical s...

ژورنال: سلامت و محیط زیست 2019

Background and Objective: Surface water and underground water quality in countries that facing dehydration have increased the interest of the community to use Household Water Treatment devices. The aim of this study was the evaluation of the quality of drinking water of Household Water Treatment devices and general distribution network in Garmsar, which is under the control of the water safety ...

Journal: :Journal of toxicology. Clinical toxicology 1997
J Pronczuk de Garbino J A Haines D Jacobsen T Meredith

Important developments concerning the role of antidotes in managing poisoning cases have taken place in recent decades due to new toxicodynamic and toxicokinetic studies and to growing international concern regarding the effectiveness of antidotes. A number of activities are carried out by the International Programme on Chemical Safety which aim to: (1) evaluate their effectiveness in clinical ...

2016
Stanley T Crooke Brenda F Baker T Jesse Kwoh Wei Cheng Dan J Schulz Shuting Xia Nelson Salgado Huynh-Hoa Bui Christopher E Hart Sebastien A Burel Husam S Younis Richard S Geary Scott P Henry Sanjay Bhanot

The common chemical and biological properties of antisense oligonucleotides provide the opportunity to identify and characterize chemical class effects across species. The chemical class that has proven to be the most versatile and best characterized is the 2'-O-methoxyethyl chimeric antisense oligonucleotides. In this report we present an integrated safety assessment of data obtained from cont...

2000
David W. Mosley

(CPI), by their very nature, involve chemical reactions and the handling of reactive chemicals. As such, there are inherent dangers involved in the CPI that can lead to catastrophic consequences. Much activity is directed towards avoiding these types of events. Safety is not the only driver in process development. Chemical processes are developed to earn a positive return on investment. The ove...

ژورنال: سلامت کار ایران 2008
عدل, جواد, قهرمانی, بوالفضل, نسل سراجی, جبرائیل,

  Background and aims   Prevention of potential accidents and safety promotion in chemical processes requires systematic safety management in them. The main objective of this study was analysis of important process equipment components failure modes and effects in H2S and CO2  isolation from extracted natural gas process.   Methods   This study was done in sweetening unit of an Iranian gas refi...

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