A synthetic peptide, KFFKFFKFFK [corrected], consisting of cationic lysine residues and hydrophobic phenylalanine residues was found to sensitize gram-negative bacteria to hydrophobic and amphipathic antibiotics. At a concentration of 3 micrograms/ml, it decreased the MIC of rifampin for smooth, encapsulated Escherichia coli by a factor of 300. Other susceptible bacterial species included Enter...

PURPOSE To evaluate the effects of a novel mouthrinse containing 0.07% high bioavailable cetylpyridinium chloride (Crest Pro-Health Rinse) on the development of gingivitis and plaque versus a placebo control over a period of 6 months. METHODS This was a randomized, 6-month, placebo-controlled, parallel groups, double blind, single center clinical trial. One hundred thirty-nine generally healt...

An improved method for the direct counting of basophil leucocytes from venous or capillary blood is described. The method is based upon the use of cetylpyridinium chloride to lyse the erythrocytes and render the muco-polysaccharides of the granule insoluble. Aluminium sulphate is used to mordant toluidine blue to the granules. Our knowledge of the role of the basophil leucocytes in disease has ...

The oral cavity is particularly susceptible to viral infections that are self-recovering in most cases. However, complications may appear severe cases and/or immunocompromised subjects. Cetylpyridinium chloride (CPC)-containing mouthwashes able decrease the infectivity of SARS-CoV-2 virus by disrupting integrity envelope. Here, we show CPC, as active ingredient contained commercialized, exerts ...

Positively charged (cetylpyridinium chloride), negatively (sodium dodecyl sulfate), and non-charged (polyethylene glycol) surfactants are used as potential foulant in reverse electrodialysis systems supplying seawater river freshwater. Fouling tendency of the foulants to ion-exchange membranes is investigated terms adsorption by electromigration, electrostatic attraction, macromolecule interact...