Background: Preterm birth is a major cause of neonatal and infant illness mortality in developing countries. It associated with severe suffering for both the mother neonate as well long-term disabilities; hence interventions to prevent preterm are critical. Therefore, accurate markers determining whether pregnant woman at high risk delivery could lead better surveillance more timely interventio...

PURPOSE Imiquimod is a Toll-like receptor 7 agonist used topically to treat external genital warts and basal cell carcinoma. We examined the combination of topical imiquimod with intramuscular administration of CRT/E7, a therapeutic human papillomavirus (HPV) vaccine comprised of a naked DNA vector expressing calreticulin fused to HPV16 E7. EXPERIMENTAL DESIGN Using an orthotopic HPV16 E6/E7(...

BACKGROUND Being able to predict preterm birth is important, as it may allow a high-risk population to be selected for future interventional studies and help in understanding the pathways that lead to preterm birth. OBJECTIVE To investigate the accuracy of novel biomarkers to predict spontaneous preterm birth in women with singleton pregnancies and no symptoms of preterm labour. SEARCH STRA...

Cervicovaginal mucus is a mixture of mucins, ions, salts, and water, the proportions which change during reproductive cycle. It suspected that this emits an important volatile signal indicative state female. The objective study was to identify organic compounds (VOC) in bovine cervicovaginal are modulated estrous cycle could potentially be used as biomarkers estrus ovulation. collected from cro...