The lung is a distant metastatic site of gynecologic cancers. These metastases have clinical characteristics which can be solitary, multiple, solid, or manifest by pleural effusion. Diagnosing and managing metastasis challenging because each type gynecological cancer has different characteristics. Some cancers tumor markers that help diagnose metastasis; however, others do not them. options for...

Claudins are the main protein components of tight junctions (TJs) which function as selective barriers by controlling paracellular diffusion, maintain cellular polarity and play a role in signal transduction. The expression pattern of the 24 known members of the claudin family proved to be organ and tissue specific. The up- or downregulation of individual claudins has been described, especially...

Atypical polypoid adenomyoma (APA) is a rare polypoid tumor of the uterus composed of atypical endometrial glands and smooth muscle cells. Concomitant development of endometrial adenocarcinoma in APA remains infrequent. We report a case of the coexistence of endometrioid adenocarcinoma in APA. A 41-year-old patient presented with abnormal genital bleeding. A polypoid mass was extruded from the ...

A model for predicting extrauterine tumor spread in patients with endometrial cancer
 
 Abstract
 Background: The factors undergoing staging surgery the diagnosis of cancer were investigated. Aims: study aimed to create a using demographic, surgical, and pathological predict spread.
 Methods: Included 355 final who underwent purposes. effect surgical-prognostic on was analyz...

2 patients with endometrial cancer stage II and 2 patients with cervical cancer stage Ib1 underwent totally laparoscopic radical hysterectomy (TLRH) in 2004. The patients were placed in the lithotomic position. Laparoscopy was performed through the umbilicus and three ancillary ports were placed in the diamond shaped usual position. Only bipolar coagulation was used to control bleeding. No uter...

2 patients with endometrial cancer stage II and 2 patients with cervical cancer stage Ib1 underwent totally laparoscopic radical hysterectomy (TLRH) in 2004. The patients were placed in the lithotomic position. Laparoscopy was performed through the umbilicus and three ancillary ports were placed in the diamond shaped usual position. Only bipolar coagulation was used to control bleeding. No uter...

R. J. is a 56-year-old woman with recurrent stage 1a, grade 3 endometrial carcinoma who was first diagnosed in 2011. She underwent hysterectomy and bilateral salpingo-oophorectomy with lymph node dissection. No adjuvant therapy was recommended, and she was followed every 3 months. Recurrent endometrial cancer was diagnosed in June 2012 after a left cervical lymph node biopsy showed metastatic a...

BACKGROUND Hepsin is a type II transmembrane serine protease originally identified in the human liver as a cDNA clone. Hepsin was found to be significantly overexpressed in cancer samples compared to matched various tissues (e.g. prostate, renal, ovarian carcinoma). The purpose of the present study was to examine hepsin expression and to evaluate its clinicopathological significance in endometr...

Supraclavicular lymph node metastasis from endometrial carcinoma is considerably rarer than metastasis from uterine cervical cancer. To date, there have been no reported cases regarding systematic neck dissection as a salvage treatment. In this report, we describe the neck dissection procedure carried out on a 74-year-old woman with supraclavicular lymph node metastasis. Our objective was to hi...

AIM The purpose of this study was to establish and analyze the laparoscopic technique of radical hysterectomy and para-aortic and pelvic lymphadenectomy and to retrospectively evaluate its feasibility and morbidity. PATIENTS AND METHODS During a one-year period 12 patients underwent laparoscopic radical surgical procedures for cervical or endometrial cancer. All our patients underwent radical...