Leishmaniasis is one of the major health problems and categorized as a class I disease (emerging and uncontrolled) by World Health Organization (WHO), causing highly significant morbidity and mortality. Indeed, more than 350 million individuals are at risk of Leishmania infection, and about 1.6 million new cases occur causing more than 50 thousands death annually. Because of the severe...

The plant-pathogen interaction is a multifactor process that may lead to resistance or susceptible responses of plant to pathogens. During the arms race between plant and pathogens, various biochemical, molecular and physiological events are triggered in plant cells such as ROS signaling, hormone activation and gene expression reprogramming. In plants, microRNAs (miRNAs) are key post-transcript...

The relationship between hypersensitivity and cellular resistance to infection with facultative intracellular parasites was studied in mice by using infection-immunity in tularemia as a model system. Delayed hypersensitivity to antigenic fractions of Francisella tularensis was first detected 6 to 7 days after immunization with viable F. tularensis vaccine, at which time immunity against challen...

In order to evaluate the effects of chlorella on broiler performance and immune system, an experimentwas performed by using 80 ROSS 308 male broiler chicks. The experiment was accomplished incompletely randomized design including 5 treatments with 4 replication and 4 observations in eachreplicate. The basal diet was based on corn-soybean meal (control) and without any additives. Agraded level o...

Restraint-induced stress (RS) increases histamine concentration in the brain. There is no previous report regarding the role of histamine receptors in immunomodulatory effect of RS. In the present study the role of brain histamine receptors on reduction of humoral and cellular immune function induced by RS was evaluated. For this purpose male Wistar rats (200-250 g) were immunized with sheep re...

BACKGROUND Exposure to stress modifies the humoral and cellular immunity by the activation of the hypothalamic-pituitary-adrenal axis. On one hand, this psycho-immunological theory allows the analyse of links between immunity and depression. On the other hand, the correlation between the immune response, the clinical expression in major depressive disorder (MDD) and the gender was proven. Our a...

In renal transplantation, BK-virus (BKV)-associated nephropathy has emerged as a major complication, with a prevalence of 1-10% and graft loss in >50% of cases. BKV is a member of the polyomavirus family and rarely induces apparent clinical disease in the general population. However, replication of polyomaviruses, associated with significant organ disease, is observed in patients with acquired ...

this paper presents the hardware simulation (based on vhdl code) of a multiple-fault tolerant cellular genetic algorithm. this study aims to increase the immunity of cellular genetic algorithm in multiple-fault situation. here, multiple-fault refers to the situation that seu (single event upset) occurs simultaneously at two or more bits of the chromosome and fitness registers. the fault model i...