The effect of nano selenium foliar application on some secondary metabolites Hypericum perforatum L.

The effects of polysaccharide elicitors such as chitin, pectin, and dextran on the production of phenylpropanoids (phenolics and flavonoids) and naphtodianthrones (hypericin and pseudohypericin) in Hypericum perforatum shoot cultures were studied. Nonenzymatic antioxidant properties (NEAOP) and peroxidase (POD) activity were also observed in shoot extracts. The activities of phenylalanine ammon...

In the present study, the Tangrah region located in the vicinity of GolestanNational Park was selected for exploring the changes in the amount of the secondaryessential of hypericin in Hypericum perforatum in different highlands of the easternGolestan province. The aerial flowered parts of the herb were collected randomly and inthree replications from four altitudes of 300 m, 600 m, 900 m, and ...

Alzheimer's disease is multi-component neurodegenerative disorder. Oxidative stress disrupts regular functioning of metabolism in early-onset disease. It causes Tau phosphorylation, formation neurofibrillary tangle and neuron reduction. Due to intense binding phosphorylated amino acids aluminum, it induces self-assembly deposition high degree cytoskeletal proteins, such as microtubule neurofila...

Background: Flavonoids of Hypericum perforatum are important secondary metabolites which have been widely utilized in medicine for a range of purposes. The use of methyl jasmonate (MeJA) elicitation for the enhancement of flavonoid production in cell suspension culture of H. perforatum would be an efficient alternative method for the flavonoid production. Results: MeJA influenced the cells grow...

Hypericin, an antidepressant and antiviral agent being evaluated in phase I and II trials for patients with HIV infection, is known to be a potent protein kinase C inhibitor. We have investigated its effects on cellular response to radiation via a tetrazolium-formazan cell growth rate assay using 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide and clonogenic assay in three human g...