نتایج جستجو برای: cell surface tlrs

تعداد نتایج: 2204698  

2017
Dongxiang Gu Fengxian Zhen David B. Hannaway Yan Zhu Leilei Liu Weixing Cao Liang Tang

Quantitative study of root morphological characteristics of plants is helpful for understanding the relationships between their morphology and function. However, few studies and little detailed and accurate information of root characteristics were reported in fine-rooted plants like rice (Oryza sativa L.). The aims of this study were to quantitatively classify fine lateral roots (FLRs), thick l...

Journal: :Life Sciences 2019

2016
Chengcheng Ren Qiuxiang Zhang Bart J. de Haan Hao Zhang Marijke M. Faas Paul de Vos

Although many lactic acid bacteria (LAB) influence the consumer's immune status it is not completely understood how this is established. Bacteria-host interactions between bacterial cell-wall components and toll-like receptors (TLRs) have been suggested to play an essential role. Here we investigated the interaction between LABs with reported health effects and TLRs. By using cell-lines express...

2008
Anne Månsson Lars Olaf Cardell

WINNING ABSTRACT: Asthma is disease characterized by a massive accumulation of eosinophils that release an array of tissue-damaging mediators. Respiratory viral infections are thought to be a leading cause of exacerbations of asthma. One possible explanation might be a direct activation of viral components through Toll-like receptors (TLRs), a receptor family comprising 10 different pathogen-re...

Journal: :Genetics and molecular research : GMR 2016
L Sun J J Dai W F Hu J Wang

Toll-like receptors (TLRs) can specifically identify pathogen-associated molecular patterns (PAMPs) by recognizing structural patterns in diverse microbial molecules, and can provide an effective defense against multiple microbial infectious. A variety of TLRs can be expressed on the surface of liver parenchymal as well as nonparenchymal cells. Kupffer cells are a type of hepatic nonparenchymal...

Journal: :The Journal of Experimental Medicine 2003
Benjamin N. Gantner Randi M. Simmons Scott J. Canavera Shizuo Akira David M. Underhill

Toll-like receptors (TLRs) mediate recognition of a wide range of microbial products including lipopolysaccharides, lipoproteins, flagellin, and bacterial DNA, and signaling through TLRs leads to the production of inflammatory mediators. In addition to TLRs, many other surface receptors have been proposed to participate in innate immunity and microbial recognition, and signaling through some of...

Journal: :Neuro-oncology 2006
S Farzana Hussain David Yang Dima Suki Kenneth Aldape Elizabeth Grimm Amy B Heimberger

Little is known about the immune performance and interactions of CNS microglia/macrophages in glioma patients. We found that microglia/macrophages were the predominant immune cell infiltrating gliomas ( approximately 1% of total cells); others identified were myeloid dendritic cells (DCs), plasmacytoid DCs, and T cells. We isolated and analyzed the immune functions of CD11b/c+CD45+ glioma-infil...

Journal: :Journal of innate immunity 2009
Marco Hoffmann Mirjam B Zeisel Nikolaus Jilg Glaucia Paranhos-Baccalà Françoise Stoll-Keller Takaji Wakita Peter Hafkemeyer Hubert E Blum Heidi Barth Philipp Henneke Thomas F Baumert

Toll-like receptors (TLRs) are pathogen recognition molecules activating the innate immune system. Cell surface expressed TLRs, such as TLR2 and TLR4, have been shown to play an important role in human host defenses against viruses through sensing of viral structural proteins. In this study, we aimed to elucidate whether TLR2 and TLR4 participate in inducing antiviral immunity against hepatitis...

2014
Alison Mary Rich Haizal Mohd Hussaini Venkata P. B. Parachuru Gregory J. Seymour

It is becoming increasingly apparent that the tumor microenvironment plays an important role in the progression of cancer. The microenvironment may promote tumor cell survival and proliferation or, alternatively may induce tumor cell apoptosis. Toll-like receptors (TLRs) are transmembrane proteins, expressed on immune cells and epithelial cells, that recognize exogenous and endogenous macromole...

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