Several mammalian enzymes are anchored to the outer surface of plasma membrane by a covalently attached glycosyl-phosphatidylinisitol (GPI) structure. These include acetylcholinesterase, alkalinee phosphatase and 5´-nucleotidase. Recently, it has been reported that these membrane enzymes can be solubilized into the serum by GPI-dependent PLD, under various medical disturbances such as cancer an...

Introduction: Human embryonic stem cells (hESCs) are pluripotent cells that can proliferate and differentiate to many cell types. Their electrophysiological properties have not yet been chracterzed. In this study, the passive properties (such as resting membrane potential, input resistance and capacitance) and the contribution of delayed rectifier K+ channel currents to the membrane conducta...

introduction: the neuroprotective role of opioid morphine against 6-hydroxydopamineinduced cell death has been demonstrated. however, the exact mechanism(s) underlying such neuroprotection, especially the role of subtype receptors, has not yet been fully clarified. methods: here, we investigated the effects of different opioid agonists on 6-ohda-induced neurotoxicity in human neuroblastoma sh-s...

A novel proton exchange membrane has been prepared using sulfonated poly(styrene-divinylbenzene) resin(SPSDR)–polyethylene(PE). The membrane is characterized by FT-IR, SEM and TGA/DSC. Water uptake, oxidative resistance, ionic conductivity and methanol permeability are measured to evaluate its performance in a direct methanol fuel cell. The on-set degradation temp...

Several mammalian enzymes are anchored to the outer surface of plasma membrane by a covalently attached glycosyl-phosphatidylinisitol (GPI) structure. These include acetylcholinesterase, alkalinee phosphatase and 5´-nucleotidase. Recently, it has been reported that these membrane enzymes can be solubilized into the serum by GPI-dependent PLD, under various medical disturbances such as cancer an...

Crocin, the main constituent of saffron (Crocus sativus L.), is a natural carotenoid which is known for its antioxidant activity. Liver as the organ that metabolizes many chemicals is one of the first position that is at risk of environmental pollutants. It is clear that compounds that exhibit antioxidant properties, scavenging of free radicals and inhibition of lipid peroxidation are expected ...

Abstract Cell membrane vesicles, as delivery carriers of drugs or biological agents in vivo, are an important therapeutic mode the study disease treatment. Tumor membrane-derived vesicles have been widely used tumor therapy because their good enrichment effect. The most common method is surface nanoparticles coated with cell membrane, which can effectively prolong circulation time particles blo...

purpose: to develop a nanofibrous polycaprolacton (pcl) substrate for limbal stem cell (lsc) expansion that can serve as a potential alternative substrate to replace human amniotic membrane. methods: the human limbal stem cells (lscs) were used to evaluate the biocompatibility of substrates (nanofibrous scaffold, and human amniotic membrane) regarding cellular phenotypic profile, viability, pro...