Sonoporation has been exploited as a promising nonviral strategy for intracellular delivery of drugs and genes. The technique utilizes ultrasound application, often facilitated by the presence of microbubbles, to generate transient, nonspecific pores on the cell membrane. However, due to the complexity and transient nature of ultrasound-mediated bubble interaction with cells, no direct correlat...

The sonication of ionic organic liquids leads to decomposition of the liquids. Multibubble sonoluminescence spectra and headgas analysis reveal a variety of decomposition products from the sonolysis of N,N'-dialkylimidazolium ionic liquids. The decomposition is a result of acoustic cavitation, which generates localized hot spots from the implosive collapse of bubbles in the ionic liquids. Despi...

• Kelvin-Helmholtz Instability forms in cavitating microchannels. Governs Cavitation Cloud Shedding Microchannels. This is the third mechanism of cavitation cloud shedding. High Speed and X-ray visualization was performed. Simple model for flow developed. The paper shows inside a micro-Venturi channel. While initial aim study to establish supercavitating conditions micro-Venturi, yet we found t...

Neither the influence of high shear rates nor the impact of cavitation on protein aggregation is fully understood. The effect of cavitation bubble collapse-derived hydroxyl radicals on the aggregation behavior of human serum albumin (HSA) was investigated. Radicals were generated by pumping through a micro-orifice, ultra-sonication, or chemically by Fenton's reaction. The amount of radicals pro...

We use time-resolved imaging to examine the lysis dynamics of non-adherent BAF-3 cells within a microfluidic channel produced by the delivery of single highly-focused 540 ps duration laser pulses at lambda = 532 nm. Time-resolved bright-field images reveal that the delivery of the pulsed laser microbeam results in the formation of a laser-induced plasma followed by shock wave emission and cavit...

Cavitation erosion is induced by the penetrating pressure from implosion of cavitation bubbles nearby solid boundary. The bubble evolution and subsequent collapse are especially important to evaluate degradation boundary materials. dynamics equation taking into account influence distance between formulated investigate effect wall on process. fluctuation slapping forces adopted dynamic character...

Light emission from bubbles in liquids has received increased attention with the advent of single bubble levitation in sound fields [1]. In this Letter we present investigations of the light emission from single collapsing cavitation bubbles: single cavitation bubble luminescence (SCBL). Our method makes use of focused laser light to produce largely empty bubbles in a liquid, a method used earl...

In the current paper, indicative results of the flow simulation during the opening phase of a Diesel injector are presented. In order to capture the complex flow field and cavitation structures forming in the injector, Large Eddy Simulation has been employed, whereas compressibility of the liquid was included. For taking into account cavitation effects, a two phase homogenous mixture model was ...