OBJECTIVES To describe a case of neuroleptic malignant syndrome following antipsychotic treatment of catatonia, highlighting the potentially serious complications of this rare adverse drug reaction. METHODS We present a case report of a patient who developed this syndrome with various sequelae. RESULTS The patient developed neuroleptic after being treated with lorazepam and olanzapine for c...

391 ISSN 1758-2008 10.2217/NPY.13.41 © 2013 Future Medicine Ltd Neuropsychiatry (2013) 3(4), 391–399 Summary Catatonia is common, and has an incidence in psychiatric inpatients from the USA, UK and other western countries of 10%. Half of the patients with catatonia suffer from bipolar disorder and approximately 10% have a diagnosis of schizophrenia. With multiple possible etiologies, a unifying...

The symptoms of malignant (lethal) catatonia has been reported similar to initial symptoms of anti-NMDAR encephalitis. Subsequently, this autoimmune limbic encephalitis has been noticed in many psychiatrists. We have experienced several cases with malignant catatonia having anti-NMDAR antibody without clinical signs of encephalitis. Thereafter, we have also found anti-NMDAR antibody positive pa...

BACKGROUND Catatonia is a psychomotor syndrome that can be characterized by behavioural, affective and motor abnormalities. In order to reveal further underlying pathophysiological mechanisms of psychomotor disturbances in catatonia we investigated neuropsychological function and regional cerebral perfusion (r-CBF) in a combined study. METHODS Ten catatonic patients were investigated with Tc-...

Many residents in psychiatry may go through training never having to make a diagnosis of catatonia, even though they may have to make a diagnosis of catatonic excitement in schizophrenia or a mood disorder with catatonic features. Catatonia due to a general medical condition is less likely to be diagnosed by the psychiatrist. Catatonia was described as far back as 1874 by Karl Kahlbaum, who vie...

Catatonia is an infrequent but severe condition in young people. Organic diseases may be associated and need to be investigated though no specific recommendations and guidelines are available. We extensively reviewed the literature of all the cases of organic catatonia in children and adolescents from January 1969 to June 2007. We screened socio-demographic characteristics, organic diagnosis, c...

Sir, We read with interest the study by Payee et al. (1999). Authors remark that no study on the treatment of catatonia with lorazepam has been carried out in India. In this context, we would like to mention that a similar but more exhaustive study has been conducted by us on a larger patient population at Central Institute of Psychiatry, Ranchi. We share a few findings from our study, which is...

Paliperidone is an atypical antipsychotic medication commonly used to treat schizophrenia, schizoaffective disorder, and bipolar disorder. It a metabolite of risperidone has similar mechanism action, primarily blocking dopamine 2 receptors (D2 receptors) in the brain. various adverse effects, including extrapyramidal symptoms, weight gain, metabolic disturbances. Catatonia rare but severe side ...