POEMS syndrome is a rare paraneoplastic syndrome secondary to a plasma cell dyscrasia. Recognition of the complex of a combination of peripheral neuropathy, organomegaly, endocrinopathy, monoclonal plasmaproliferative disorder, skin changes, papilledema, extravascular volume overload (peripheral edema, pleural effusions, ascites), sclerotic bone lesions, thrombocytosis, Castleman disease is the...

Castleman disease (CD) is a lymphoproliferative disorder of unknown etiology that is associated with the development of secondary tumors, including B-cell lymphoma. Human herpesvirus 8 (HHV-8) (Kaposi's sarcoma-associated herpesvirus) sequences have been described in some cases of multicentric Castleman disease (MCD). Using a monoclonal antibody against an HHV-8-latent nuclear antigen, we show ...

BACKGROUND We report a case of unicentric Castleman disease, a rare type of benign proliferation of lymphoid tissue. We present an uncommon disease that was managed effectively using laparoscopy. CASE PRESENTATION A 32-year-old woman presented with left-sided flank pain. A large retroperitoneal mass was detected in the left renal hilum close to the renal vessels. Laparoscopic removal of the m...

introduction: castleman's disease is a rare lymphoproliferative disorder which may be confused with other causes of lymphadenopathy. case report: here we report a case of unicentric castleman's disease presenting with cervical lymphadenopathy. the patient was treated with complete surgical excision of lesion and was disease free at the time of reporting this article. this case has bee...

Results Patient was taken up for surgery. Thoracotomy revealed a firm well encapsulated 4*4 cm, highly vascular, mass in close relation to hilar structures, crossing the oblique fissure into the lower lobe and with no invasion of hilar structures, or mediastinal lymphadenopathy. The mass was removed en bloc with a pneumonectomy. Histopathology confirmed a hyaline vascular type of Castleman tumo...

Kingston, Diehl, Kirk, and Castleman [Kingston, J., Diehl, R. L., Kirk, C. J., Castleman, W.A., 2008. On the perceptual structure of distinctive features: The [voice] contrast. Journal of Phonetics, 36, 28–54] present a sophisticated experimental design and detection theoretic analysis of the internal auditory structure of phonological contrasts. However, a potentially important aspect of multi...

Background Idiopathic multicentric Morbus Castleman (iMCD) is a very rare disease with broad spectrum of symptoms and complex histopathological diagnosis. An expert meeting in 2017 by Fajgenbaum et al. defined new criteria for the diagnosis iMCD. Estimations prevalence German population do not exist yet. As lymphadenopathy often occurs primarily head neck region patients are frequently referred...