OBJECTIVES We sought to determine the relative impact of diabetes mellitus on prognosis in ischemic compared with nonischemic cardiomyopathy. BACKGROUND Ischemic myocardium is characterized by increased reliance on aerobic and anaerobic glycolysis. Because glucose utilization by cardiomyocytes is an insulin-mediated process, we hypothesized that diabetes would have a more adverse impact on mo...

UNLABELLED The cause of cardiomyopathy in patients infected with the human immunodeficiency virus (HIV) remains largely unknown, although a number of predisposing factors have been identified. Malnutrition has been postulated to be a contributory factor, but the association of anthropometric measures of nutritional status with HIV-associated cardiomyopathy has not been established. METHOD We ...

Aims: Dilated cardiomyopathy often shows left ventricular systolic dysfunction, although histologically it always exhibits non-specific abnormality. We hypothesized that myocyte sound speed might be altered due to incomplete protein accumulation in cells. Methods and Results: Ninety eight biopsied samples were obtained from 49 patients comprising 43 with clinical dilated cardiomyopathy and 6 wi...

AIM Hospital discharges with a diagnosis of cardiomyopathy have more than doubled in Sweden since 1987. We validated the cardiomyopathy diagnoses over this time period to investigate that the increase was real and not a result of improved recognition of the diagnosis and better diagnostic methods. METHODS AND RESULTS Every fifth year from 1989 to 2009, records for all patients with a cardiomy...

Takotsubo cardiomyopathy is an acute cardiac condition characterized by transient systolic dysfunction of the left ventricular apex and mid-ventricle. Documented EKG presentations for Takotsubo cardiomyopathy include ST-segment elevation or T-wave inversion. These EKG presentations are included in the diagnostic requirements for Takotsubo cardiomyopathy. This paper presents two cases of atypica...

Introduction: Cardiomyopathy is the disorder of heart muscles which can be dilated, hypertrophic or restrictive type. Dilated cardiomyopathy caused by genetic and non-genetic causes but many are still not known. Echocardiography an important imaging technique to diagnose manage dilated cardiomyopathy.
 Aims: This study aims assess clinical echocardiographic findings among patients with Met...

Cardiomyopathy as the initial presentation of phaeochromocytoma (PCA) is uncommon. Diagnostic work-up and perioperative management may be challenging within this context. We report three cases of PCA presenting with cardiomyopathy to illustrate the pitfalls in diagnosis and management. None of the patients had typical adrenergic symptoms and all three were established on beta-blockers prior to ...

Ventricular tachyarrhythmias are common in hypertrophic cardiomyopathy that may lead to syncope and sudden death. Bradyarrhythmia such as atrioventricular conduction disturbance, a relatively rare complication associated with hypertrophic cardiomyopathy, may also cause syncope and sudden death in hypertrophic cardiomyopathy. We report a 28-year old man who was diagnosed as a case of hypertrophi...

Introduction: Noncompaction cardiomyopathy (NccM) is a rare form of cardiomyopathy. the American Heart Association classified it as a genetic cardiomyopathy. the pathogenesis of this condition is attributed to the failure of trabecular myocardium to compact and underdeveloped microcoronary circulation. case report: We present a case of a 72-year-old African American female who presented with sh...

Hepatitis C virus (HCV) has been reported to be associated with cardiomyopathy. However, the mechanism of cardiomyopathy in chronic HCV infection is still unclear. Therefore, we investigate the development of cardiomyopathy in mice transgenic for the HCV-core gene. After the age of 12 months, mice developed cardiomyopathy that appeared as left ventricular dilatation, and systolic and diastolic ...