Although human cardiomyocytes (CMs) are capable of some cell division, this response is neither sufficient to repair damaged cardiac tissue nor efficient to compensate for pathological stress. Danio rerio (zebrafish) CMs have been shown to have high proliferative capability to completely repair hearts after injury; however, no reports have focused on their physiological and cellular response to...

BACKGROUND Cardiac perforation is a recognized complication of catheter ablation procedures, most commonly encountered during ablation of atrial fibrillation. The study aims to investigate the incidence, management, and hospital outcomes of cardiac perforation complicating catheter ablation for ventricular arrhythmias. METHODS AND RESULTS Consecutive patients undergoing catheter ablation for ...

Shahani, Rohan, John G. Marshall, Barry B. Rubin, Ren-Ke Li, Paul M. Walker, and Thomas F. Lindsay. Role of TNF-a in myocardial dysfunction after hemorrhagic shock and lower-torso ischemia. Am. J. Physiol. Heart Circ. Physiol. 278: H942–H950, 2000.—Ruptured abdominal aortic aneurysm (RAAA) repair, a combination of hemorrhagic shock and lower-torso ischemia, is associated with a 50–70% mortality...

Shahani, Rohan, John G. Marshall, Barry B. Rubin, Ren-Ke Li, Paul M. Walker, and Thomas F. Lindsay. Role of TNF-a in myocardial dysfunction after hemorrhagic shock and lower-torso ischemia. Am. J. Physiol. Heart Circ. Physiol. 278: H942–H950, 2000.—Ruptured abdominal aortic aneurysm (RAAA) repair, a combination of hemorrhagic shock and lower-torso ischemia, is associated with a 50–70% mortality...

Iatrogenic aortic valve injury during non-aortic cardiac surgery is an infrequent complication. regurgitation (AR) has been reported after mitral repair, septal myomectomy, closure of the ventricular defect, and atrial defect repair. Various causes have for AR surgery. Perforation leaflet a common cause AR. Other are tension retraction due to inadvertent suture placement. A few previous case re...

BACKGROUND Sinus of Valsalva aneurysm (SVA) is an uncommon cardiac defect accounting for only 1% of congenital cardiac anomalies and the most common complication is ruptured into the atrium or ventricle. Very late recurrence of ruptured SVA after patch repair is extremely rare. CASE PRESENTATION We present a case of 57-year-old man had received repair for ruptured Sinus of Valsalva aneurysm a...

OBJECTIVE To determine if the Revised Cardiac Risk Index (Lee) is useful for stratification of patients by risk of both perioperative cardiac morbidity and long-term all-cause mortality in the setting of endovascular repair of abdominal aortic aneurysms. DESIGN This study was designed as a retrospective review. SETTING It was conducted at a single academic medical institution. PARTICIPANT...

Heart failure after myocardial infarction (MI) continues to be the most prevalent cause of morbidity and mortality worldwide. Although pharmaceutical agents and interventional strategies have contributed greatly to therapy, new and superior treatment modalities are urgently needed given the overall disease burden. Stem cell-based therapy is potentially a promising strategy to lead to cardiac re...